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NCT06279234 · ClinicalTrials.gov registry record · Phase 1
A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus
A Phase 1 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
NCT06279234: Completed Phase 1 study, sponsored by Pfizer.
NCT06279234 is a Phase 1 study that has completed, run by Pfizer. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06279234, a Phase 1 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
Study Summary
The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple escalating oral doses of PF-06954522 in adult participants with inadequately controlled type 2 diabetes mellitus (T2DM) on metformin (Part A) and optionally in non-diabetic participants with obesity (Part B).
Interventions
- DRUG Placebo
- DRUG Midazolam
- DRUG Omeprazole
- DRUG Rosuvastatin
- DRUG PF-06954522
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-02-20 |
| Est. Completion | 2025-04-11 |
| Phase | Phase 1 |
What the finished NCT06279234 record still lists
NCT06279234 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT06279234 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06279234 about?
NCT06279234 is a clinical study titled "A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus". The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple escalating oral doses of PF-06954522 in adult participants with inadequately controlled type 2 diabetes mellitus (T2DM) on metformin (Part A) and optionally in non-diabetic p...
What is the current status of trial NCT06279234?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2024-02-20. Estimated completion is 2025-04-11.
What interventions are being tested in trial NCT06279234?
The interventions under investigation include: Placebo (DRUG), Midazolam (DRUG), Omeprazole (DRUG), Rosuvastatin (DRUG), PF-06954522 (DRUG).
Who is sponsoring clinical trial NCT06279234?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06279234's enrollment target sits among peer trials
50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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