Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06267521 · ClinicalTrials.gov registry record · NA
The STRENGTHEN Study
A NA study of Emotional Regulation and Cognitive Flexibility, sponsored by University of Wisconsin, Madison.
- Recruiting
- Registry status
- NA
- Development phase
- 96
- Enrollment target
- 1
- Study location
NCT06267521: Recruiting NA study of Emotional Regulation and Cognitive Flexibility, sponsored by University of Wisconsin, Madison.
NCT06267521 is a NA study of Emotional Regulation and Cognitive Flexibility that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 96 participants, below the 469-participant average among 11 other Emotional Regulation trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06267521, a NA study of Emotional Regulation and Cognitive Flexibility, is actively recruiting participants, sponsored by University of Wisconsin, Madison.
- RECRUITING
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
- 1
- Study location
Study Summary
This study uses two different types of interventions including electrical brain stimulation delivered during sleep, and brief, daily meditation training. The investigators are trying to figure out whether these techniques, either alone or in combination with each other, can positively impact the brain networks that support our ability to think flexibly and to regulate our emotions. 48 participants will be enrolled into each of 2 phases and can expect to be on study for up to 9 months.
Primary Outcome
The PHQ-9 is a 9-item inventory asking participants to rate from 0 (not at all) to 3 (nearly everyday) the frequency and intensity of depressive symptoms experienced by the respondent over the preceding two-week period. Scores range from 0 to 27 where higher scores indicate poorer patient health. Participants with scores greater than 15 will be excluded from study.
Conditions Studied
Interventions
- OTHER Healthy Minds Program
- OTHER Sham Meditation Didactic Material
- DEVICE Sham Stimulation in Lab
- DEVICE Stimulation in Lab
- DEVICE MRI Scanner
Study Locations (1)
Wisconsin
- Center for Healthy Minds - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2024-03-06 |
| Est. Completion | 2026-04 |
| Phase | NA |
What NCT06267521 shows while recruiting
NCT06267521 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 96 participants, a relatively small participant target, below the 469-participant average among 11 other Emotional Regulation trials with a reported enrollment target (80% lower).
The record links to 2 conditions, with Emotional Regulation appearing as the primary indexed condition, and to 5 interventions - of which Healthy Minds Program is the first listed.
NCT06267521 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06267521 about?
NCT06267521 is a clinical study titled "The STRENGTHEN Study". This study uses two different types of interventions including electrical brain stimulation delivered during sleep, and brief, daily meditation training. The investigators are trying to figure out whether these techniques, either alone or in combination with each other, can positively impact the bra...
What is the current status of trial NCT06267521?
This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2024-03-06. Estimated completion is 2026-04.
What conditions does trial NCT06267521 study?
This clinical trial studies the following conditions: Emotional Regulation, Cognitive Flexibility.
What interventions are being tested in trial NCT06267521?
The interventions under investigation include: Healthy Minds Program (OTHER), Sham Meditation Didactic Material (OTHER), Sham Stimulation in Lab (DEVICE), Stimulation in Lab (DEVICE), MRI Scanner (DEVICE).
Who is sponsoring clinical trial NCT06267521?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06267521 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Emotional Regulation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06267521's enrollment target sits among peer trials
96 6th of 11 higher than 5 of 11 other Emotional Regulation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Emotional Regulation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families
RECRUITING · NA
-
Students With Involved Families and Teachers
RECRUITING · NA
-
Improving Minority Health Through Biofeedback and Stress Reduction
RECRUITING · NA
-
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
ACTIVE NOT RECRUITING · NA
-
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
ACTIVE NOT RECRUITING · NA
-
Dyadic Neurofeedback for Development of Healthy Emotion Regulation in Youth
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03401762 · 96 participants · NA
Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
- NCT03471260 · 96 participants · Phase 1
Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies
- NCT03549559 · 96 participants · NA
Imaging Histone Deacetylase in the Heart
- NCT03841058 · 96 participants · Phase 2
Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI