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NCT06262477 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants

A Phase 1 study, sponsored by Biogen.

Completed
Registry status
Phase 1
Development phase
300
Enrollment target

NCT06262477: Completed Phase 1 study, sponsored by Biogen.

NCT06262477 is a Phase 1 study that has completed, run by Biogen. The registered enrollment target is 300 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (400% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06262477, a Phase 1 study, has completed, sponsored by Biogen.

COMPLETED
Registry status
Phase 1
Development phase
300 participants
Enrollment target

Study Summary

The primary objective of the study is to show equivalence in pharmacokinetics (PK) of BIIB800 and Actemra following SC administration of a single dose to healthy male participants. The secondary objective of the study is to evaluate PK over time, clinical safety, pharmacodynamic (PD) profiles and immunogenicity of BIIB800 and Actemra.

Interventions

  • DRUG BIIB800
  • DRUG Actemra

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2024-01-02
Est. Completion 2024-10-04
Phase Phase 1
Biogen

334 total trials

What the finished NCT06262477 record still lists

NCT06262477 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (400% higher).

The record links to 0 conditions, and to 2 interventions - of which BIIB800 is the first listed.

NCT06262477 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06262477 about?

NCT06262477 is a clinical study titled "A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants". The primary objective of the study is to show equivalence in pharmacokinetics (PK) of BIIB800 and Actemra following SC administration of a single dose to healthy male participants. The secondary objective of the study is to evaluate PK over time, clinical safety, pharmacodynamic (PD) profiles and im...

What is the current status of trial NCT06262477?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 300 participants. The study started on 2024-01-02. Estimated completion is 2024-10-04.

What interventions are being tested in trial NCT06262477?

The interventions under investigation include: BIIB800 (DRUG), Actemra (DRUG).

Who is sponsoring clinical trial NCT06262477?

This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06262477's enrollment target sits among peer trials

300 124th of 2000 higher than 1,867 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06262477, the US trial registry maintained by the National Library of Medicine. NCT06262477 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.