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NCT06242444 · ClinicalTrials.gov registry record · NA
An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel
A NA study of Tooth Erosion, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 33
- Enrollment target
- 1
- Study location
NCT06242444: Completed NA study of Tooth Erosion, sponsored by HALEON.
NCT06242444 is a NA study of Tooth Erosion that has completed, run by HALEON. The registered enrollment target is 33 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06242444, a NA study of Tooth Erosion, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the ability of an experimental dentifrice containing 1150 parts per million (ppm) fluoride to remineralize acid-softened dental enamel and help prevent further demineralization compared to a 0 ppm fluoride placebo dentifrice and a marketed, fluoride-containing dentifrice (Reference Dentifrice).
Primary Outcome
%SMHR was used to measure the ability of the dentifrice to remineralize enamel. Previously demineralized, sterilized bovine enamel specimens were placed intra orally using a palatal appliance. The enamel specimens were exposed to the dentifrice treatments in the mouth during the treatment application and allowed to remineralize intra orally under the action of the participant's saliva. The specimens were then removed from the palatal appliance and the extent of remineralization was evaluated usi
Conditions Studied
Interventions
- DRUG Experimental Dentifrice
- DRUG Placebo Control Dentifrice
- DRUG Reference Dentifrice
Study Locations (1)
Indiana
- Oral Health Research Institute - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2024-02-26 |
| Est. Completion | 2024-05-07 |
| Phase | NA |
What the finished NCT06242444 record still lists
NCT06242444 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Tooth Erosion appearing as the primary indexed condition, and to 3 interventions - of which Experimental Dentifrice is the first listed.
NCT06242444 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT06242444 about?
NCT06242444 is a clinical study titled "An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel". The purpose of this study is to investigate the ability of an experimental dentifrice containing 1150 parts per million (ppm) fluoride to remineralize acid-softened dental enamel and help prevent further demineralization compared to a 0 ppm fluoride placebo dentifrice and a marketed, fluoride-contai...
What is the current status of trial NCT06242444?
This trial is currently completed. It is a NA study. The enrollment target is 33 participants. The study started on 2024-02-26. Estimated completion is 2024-05-07.
What conditions does trial NCT06242444 study?
This clinical trial studies the following conditions: Tooth Erosion.
What interventions are being tested in trial NCT06242444?
The interventions under investigation include: Experimental Dentifrice (DRUG), Placebo Control Dentifrice (DRUG), Reference Dentifrice (DRUG).
Who is sponsoring clinical trial NCT06242444?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06242444 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06242444's enrollment target sits among peer trials
33 1574th of 2000 higher than 423 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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