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NCT06221839 · ClinicalTrials.gov registry record
Structural Racism, Reward Related Decision Making and Substance Use Risk
A clinical trial of Structural Racism and Substance Use Risk, sponsored by Columbia University.
- Recruiting
- Registry status
- 72
- Enrollment target
- 2
- Study locations
NCT06221839 is a study of Structural Racism and Substance Use Risk that is actively recruiting participants, run by Columbia University. The registered enrollment target is 72 participants. The trial reports 2 study locations across 2 states.
The verdict
NCT06221839, a study of Structural Racism and Substance Use Risk, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 72 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this observational study, which has a pilot phase (R61) and a second, larger phase (R33), is to learn about the impact of indicators of structural racism (SR) on substance use risk in Puerto Rican adolescents living in the mainland US and in Puerto Rico. To do this, we will look at how indicators of SR relate to brain structure, brain function during reward-related choices, belief in a just world, and substance use risk indicators in Puerto Rican adolescents living in the mainland US (mostly in New York) and in Puerto Rico (mostly in San Juan). We are currently focused on the R61 (pilot) phase. This pilot phase aims to answer the question: Is there a relationship between indicators of SR and brain structure, brain function during reward-related decision making, and belief in a just world? If we are able to establish a relationship between SR indicators and outcomes, we will continue to the second phase of the study at that time. We will be collecting data from a total of 72 adolescents and their parents; n=36 in NY; n=36 in PR). Participation in the research study will include: 1. an interview with the parent or caregiver (approximately 2.5 hours) regarding the child's demographics, mental health symptoms, past experiences, the parent or caregiver's relationship with the child, as well as cultural values and acculturation; 2. an interview with the child (approximately 2.5 hours) regarding the child's past experiences, their current beliefs, personality traits and mental health symptoms; 3. an MRI scan for the child including task-based, structural and resting-state functional connectivity (approximately 1 hour).
Conditions Studied
Study Locations (2)
New York
- Columbia University Irving Medical Center - New York
Other
- University of Puerto Rico, Medical Sciences Campus - San Juan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2026-02-03 |
| Est. Completion | 2027-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06221839
The ClinicalTrials.gov registry entry for NCT06221839 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Structural Racism appearing as the primary indexed condition, and to 0 interventions.
NCT06221839 reports 2 study locations spanning 2 distinct geographic areas - top geographies include New York, Other.
Frequently Asked Questions
What is clinical trial NCT06221839 about?
NCT06221839 is a clinical study titled "Structural Racism, Reward Related Decision Making and Substance Use Risk". The goal of this observational study, which has a pilot phase (R61) and a second, larger phase (R33), is to learn about the impact of indicators of structural racism (SR) on substance use risk in Puerto Rican adolescents living in the mainland US and in Puerto Rico. To do this, we will look at how i...
What is the current status of trial NCT06221839?
This trial is currently recruiting. The enrollment target is 72 participants. The study started on 2026-02-03. Estimated completion is 2027-07.
What conditions does trial NCT06221839 study?
This clinical trial studies the following conditions: Structural Racism, Substance Use Risk.
Who is sponsoring clinical trial NCT06221839?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06221839 being conducted?
This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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