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NCT06208631 · ClinicalTrials.gov registry record · NA
Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis
A NA study of Osteoarthritis, Knee, sponsored by Stanford University.
- Recruiting
- Registry status
- NA
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT06208631: Recruiting NA study of Osteoarthritis, Knee, sponsored by Stanford University.
NCT06208631 is a NA study of Osteoarthritis, Knee that is actively recruiting participants, run by Stanford University. The registered enrollment target is 31 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06208631, a NA study of Osteoarthritis, Knee, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
This study investigates how well individuals with knee osteoarthritis can learn to alter their calf muscle activation using haptic biofeedback while walking and evaluates how these changes affect knee loading. Prior research has utilized musculoskeletal simulations to determine that reducing the activation of one of the calf muscles, the gastrocnemius, can have a large impact on reducing knee loading. However, this has not been tested in individuals with knee osteoarthritis. In this study, participants will be trained to alter the activation of their gastrocnemius muscle, by receiving haptic feedback after each step. The feedback will indicate how the participant changed their muscle activation relative to baseline. Some participants will train on a treadmill in the laboratory for up to two sessions, with 30 minutes of walking with feedback in each session. If a participant can learn to adjust their muscle activation in the first training session, they will be able to complete the second training session. Other participants will train outside the laboratory for one session with 30 minutes of walking with feedback to investigate changes in knee loading while using the new walking strategy during over-ground walking. The movement data collected during the training sessions will be used as inputs to computer simulations of the musculoskeletal system to determine if walking with the new muscle activation strategy reduces knee loading.
Primary Outcome
Knee contact force will be evaluated using motion capture data and musculoskeletal modeling and simulations, for participants that are able to reduce gastrocnemius activation.
Conditions Studied
Interventions
- BEHAVIORAL Gait retraining
Study Locations (1)
California
- Stanford Human Performance Lab - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2024-01-18 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT06208631 shows while recruiting
NCT06208631 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Gait retraining is the first listed.
NCT06208631 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06208631 about?
NCT06208631 is a clinical study titled "Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis". This study investigates how well individuals with knee osteoarthritis can learn to alter their calf muscle activation using haptic biofeedback while walking and evaluates how these changes affect knee loading. Prior research has utilized musculoskeletal simulations to determine that reducing the ac...
What is the current status of trial NCT06208631?
This trial is currently recruiting. It is a NA study. The enrollment target is 31 participants. The study started on 2024-01-18. Estimated completion is 2026-12.
What conditions does trial NCT06208631 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT06208631?
The interventions under investigation include: Gait retraining (BEHAVIORAL).
Who is sponsoring clinical trial NCT06208631?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06208631 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06208631's enrollment target sits among peer trials
31 100th of 112 higher than 13 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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