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NCT06190197 · ClinicalTrials.gov registry record · Early Phase 1
Prophylactic Antibiotics in Cystectomy With Diversion
A Early Phase 1 study of Muscle-Invasive Bladder Carcinoma and Radical Cystectomy, sponsored by University of Minnesota.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06190197: Recruiting Early Phase 1 study of Muscle-Invasive Bladder Carcinoma and Radical Cystectomy, sponsored by University of Minnesota.
NCT06190197 is a Early Phase 1 study of Muscle-Invasive Bladder Carcinoma and Radical Cystectomy that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 120 participants, roughly in line with the 117-participant average among 14 other Muscle-Invasive Bladder Carcinoma trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06190197, a Early Phase 1 study of Muscle-Invasive Bladder Carcinoma and Radical Cystectomy, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.
Primary Outcome
Test for non-inferiority of no antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.
Conditions Studied
Interventions
- DRUG Prophylactic antibiotics postoperatively.
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2024-05-13 |
| Est. Completion | 2027-10-15 |
| Phase | Early Phase 1 |
What NCT06190197 shows while recruiting
NCT06190197 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 117-participant average among 14 other Muscle-Invasive Bladder Carcinoma trials with a reported enrollment target.
The record links to 4 conditions, with Muscle-Invasive Bladder Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Prophylactic antibiotics postoperatively. is the first listed.
NCT06190197 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06190197 about?
NCT06190197 is a clinical study titled "Prophylactic Antibiotics in Cystectomy With Diversion". Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in pa...
What is the current status of trial NCT06190197?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 120 participants. The study started on 2024-05-13. Estimated completion is 2027-10-15.
What conditions does trial NCT06190197 study?
This clinical trial studies the following conditions: Muscle-Invasive Bladder Carcinoma, Radical Cystectomy, Ileal Conduit, Neobladder Diversion.
What interventions are being tested in trial NCT06190197?
The interventions under investigation include: Prophylactic antibiotics postoperatively. (DRUG).
Who is sponsoring clinical trial NCT06190197?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06190197 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Muscle-Invasive Bladder Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06190197's enrollment target sits among peer trials
120 3rd of 14 higher than 12 of 14 other Muscle-Invasive Bladder Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Muscle-Invasive Bladder Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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