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NCT06182579 · ClinicalTrials.gov registry record · Phase 1

Phase I Study of RiMO-401 With Radiation in Advanced Tumors

A Phase 1 study, sponsored by Coordination Pharmaceuticals.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT06182579: Clinical Trial Phase 1 study, sponsored by Coordination Pharmaceuticals.

NCT06182579 is a Phase 1 study that was terminated before completion, run by Coordination Pharmaceuticals. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06182579, a Phase 1 study, was terminated before completion, sponsored by Coordination Pharmaceuticals.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

This is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.

Primary Outcome

The dose limiting toxicities of RiMO-401 with palliative radiation, as assessed by CTCAEv5, will not be observed in 33% or more patients

Interventions

  • DRUG RiMO-401

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2024-02-22
Est. Completion 2025-06-16
Phase Phase 1
Coordination Pharmaceuticals

6 total trials

Why NCT06182579 stopped before completion

NCT06182579 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which RiMO-401 is the first listed.

NCT06182579 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06182579 about?

NCT06182579 is a clinical study titled "Phase I Study of RiMO-401 With Radiation in Advanced Tumors". This is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.

What is the current status of trial NCT06182579?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2024-02-22. Estimated completion is 2025-06-16.

What interventions are being tested in trial NCT06182579?

The interventions under investigation include: RiMO-401 (DRUG).

Who is sponsoring clinical trial NCT06182579?

This trial is sponsored by Coordination Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06182579's enrollment target sits among peer trials

5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06182579, the US trial registry maintained by the National Library of Medicine. NCT06182579 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.