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NCT06143670 · ClinicalTrials.gov registry record · NA
A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks
A NA study, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 159
- Enrollment target
NCT06143670: Completed NA study, sponsored by HALEON.
NCT06143670 is a NA study that has completed, run by HALEON. The registered enrollment target is 159 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06143670, a NA study, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 159 participants
- Enrollment target
Study Summary
The purpose of this clinical study is to investigate the efficacy of a dentifrice containing 0.454 percent (%) weight by weight (w/w) stannous fluoride (SnF2), on gingivitis treatment and plaque reduction, compared to a regular fluoride dentifrice after 12 weeks twice daily brushing in a population of clinically diagnosed gingivitis without undergoing dental prophylaxis.
Primary Outcome
The NBS were calculated using the bleeding index (BI) assessment. BI assesses the number of bleeding points elicited on probing as a measure of gingival condition. The BI was assessed on the facial and lingual gingival surfaces of each scorable tooth using PCP11.5B Hu-Friedy Qulix Color Coded probe. The probe was gently inserted into the gingival crevice to a depth of approximately 1 millimeter (mm) and then run around the tooth gently stretching the epithelium while sweeping from interproximal
Interventions
- DRUG Stannous fluoride toothpaste
- DRUG Sodium fluoride toothpaste
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 159 participants |
| Start Date | 2023-11-29 |
| Est. Completion | 2024-03-12 |
| Phase | NA |
What the finished NCT06143670 record still lists
NCT06143670 is an interventional study that assigns participants to a tested intervention. The registered 159 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which Stannous fluoride toothpaste is the first listed.
NCT06143670 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06143670 about?
NCT06143670 is a clinical study titled "A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks". The purpose of this clinical study is to investigate the efficacy of a dentifrice containing 0.454 percent (%) weight by weight (w/w) stannous fluoride (SnF2), on gingivitis treatment and plaque reduction, compared to a regular fluoride dentifrice after 12 weeks twice daily brushing in a population ...
What is the current status of trial NCT06143670?
This trial is currently completed. It is a NA study. The enrollment target is 159 participants. The study started on 2023-11-29. Estimated completion is 2024-03-12.
What interventions are being tested in trial NCT06143670?
The interventions under investigation include: Stannous fluoride toothpaste (DRUG), Sodium fluoride toothpaste (DRUG).
Who is sponsoring clinical trial NCT06143670?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06143670's enrollment target sits among peer trials
159 654th of 2000 higher than 1,347 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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