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NCT06140407 · ClinicalTrials.gov registry record · Phase 2

Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer

A Phase 2 study, sponsored by Vanderbilt-Ingram Cancer Center.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT06140407 is a Phase 2 study that was terminated before completion, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 1 participants.

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The verdict

NCT06140407, a Phase 2 study, was terminated before completion, sponsored by Vanderbilt-Ingram Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

This phase II trial studies how well pembrolizumab after standard treatment with radiation plus the following chemotherapy drugs: cisplatin or carboplatin, plus etoposide works in treating patients with limited stage small cell lung cancer (LS-SCLC). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab after standard treatment with radiation plus chemotherapy may increase the ability of the immune system to fight LS-SCLC.

Interventions

  • BIOLOGICAL Pembrolizumab
  • DRUG Carboplatin
  • PROCEDURE Computed Tomography
  • DRUG Cisplatin
  • DRUG Etoposide

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2024-02-14
Est. Completion 2025-05-27
Phase Phase 2

Sponsor

Vanderbilt-Ingram Cancer Center

189 total trials

What the Registry Record Tells You About NCT06140407

The ClinicalTrials.gov registry entry for NCT06140407 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt-Ingram Cancer Center, which has 189 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT06140407 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06140407 about?

NCT06140407 is a clinical study titled "Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer". This phase II trial studies how well pembrolizumab after standard treatment with radiation plus the following chemotherapy drugs: cisplatin or carboplatin, plus etoposide works in treating patients with limited stage small cell lung cancer (LS-SCLC). Immunotherapy with monoclonal antibodies, such as...

What is the current status of trial NCT06140407?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2024-02-14. Estimated completion is 2025-05-27.

What interventions are being tested in trial NCT06140407?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Carboplatin (DRUG), Computed Tomography (PROCEDURE), Cisplatin (DRUG), Etoposide (DRUG).

Who is sponsoring clinical trial NCT06140407?

This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.