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NCT06135051 · ClinicalTrials.gov registry record · Phase 1

Ultrasonic Neuromodulation for Treatment of Cognitive Impairment

A Phase 1 study, sponsored by University of Utah.

Terminated
Registry status
Phase 1
Development phase
1
Enrollment target

NCT06135051 is a Phase 1 study that was terminated before completion, run by University of Utah. The registered enrollment target is 1 participants.

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The verdict

NCT06135051, a Phase 1 study, was terminated before completion, sponsored by University of Utah.

TERMINATED
Registry status
Phase 1
Development phase
1 participants
Enrollment target

Study Summary

This study will evaluate a new form of non-invasive deep brain therapy for individuals with Alzheimer's disease. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial. The trial will evaluate brain target engagement using magnetic resonance imaging, PET imaging, and numerical scales of cognitive performance.

Interventions

  • DEVICE Diadem prototype

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2024-08-18
Est. Completion 2024-08-21
Phase Phase 1

Sponsor

University of Utah

818 total trials

What the Registry Record Tells You About NCT06135051

The ClinicalTrials.gov registry entry for NCT06135051 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Diadem prototype is the first listed.

NCT06135051 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06135051 about?

NCT06135051 is a clinical study titled "Ultrasonic Neuromodulation for Treatment of Cognitive Impairment". This study will evaluate a new form of non-invasive deep brain therapy for individuals with Alzheimer's disease. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolera...

What is the current status of trial NCT06135051?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2024-08-18. Estimated completion is 2024-08-21.

What interventions are being tested in trial NCT06135051?

The interventions under investigation include: Diadem prototype (DEVICE).

Who is sponsoring clinical trial NCT06135051?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.