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NCT06131372 · ClinicalTrials.gov registry record · Phase 2

A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

A Phase 2 study, sponsored by Novo Nordisk A/S.

Completed
Registry status
Phase 2
Development phase
626
Enrollment target

NCT06131372 is a Phase 2 study that has completed, run by Novo Nordisk A/S. The registered enrollment target is 626 participants.

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The verdict

NCT06131372, a Phase 2 study, has completed, sponsored by Novo Nordisk A/S.

COMPLETED
Registry status
Phase 2
Development phase
626 participants
Enrollment target

Study Summary

This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors. The study will compare CagriSema to the 2 medicines semaglutide and cagrilintide, when they are taken alone. It will also compare CagriSema to a "dummy" medicine (also called placebo) without any active ingredient. Participant will either get CagriSema, semaglutide, cagrilintide or placebo. Which treatment participant will get is decided by chance (like flipping a coin). Study doctor will not know which of the study medicines participant will get. For each participant, the study will last for about 35 weeks.

Interventions

  • DRUG Placebo
  • DRUG Semaglutide
  • DRUG Cagrilintide

Trial Details

FieldValue
Enrollment Target 626 participants
Start Date 2024-04-01
Est. Completion 2025-11-06
Phase Phase 2

Sponsor

Novo Nordisk A/S

431 total trials

What the Registry Record Tells You About NCT06131372

The ClinicalTrials.gov registry entry for NCT06131372 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 626 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 431 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT06131372 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06131372 about?

NCT06131372 is a clinical study titled "A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo". This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors. The study will compare CagriSema to the 2 medicines sema...

What is the current status of trial NCT06131372?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 626 participants. The study started on 2024-04-01. Estimated completion is 2025-11-06.

What interventions are being tested in trial NCT06131372?

The interventions under investigation include: Placebo (DRUG), Semaglutide (DRUG), Cagrilintide (DRUG).

Who is sponsoring clinical trial NCT06131372?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.