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NCT06106022 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease
A Phase 1 study, sponsored by Phathom Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT06106022: Completed Phase 1 study, sponsored by Phathom Pharmaceuticals.
NCT06106022 is a Phase 1 study that has completed, run by Phathom Pharmaceuticals. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06106022, a Phase 1 study, has completed, sponsored by Phathom Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
The aim of this study is to evaluate the pharmacokinetic (PK) profile of vonoprazan (10 or 20 mg once daily \[QD\]) in children ≥ 6 to \< 12 years of age who have symptomatic Gastroesophageal Reflux Disease (GERD).
Primary Outcome
Plasma pharmacokinetic (PK) parameters were estimated using a non-linear mixed effects model and were determined from the concentration-time data for all evaluable participants. Actual sampling times, rather than scheduled or nominal sampling times, were used in all computations using sampling time. Data presented based on collections on both Day 7 and Day 14.
Interventions
- DRUG Vonoprazan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2023-11-01 |
| Est. Completion | 2024-04-29 |
| Phase | Phase 1 |
What the finished NCT06106022 record still lists
NCT06106022 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 1 intervention - of which Vonoprazan is the first listed.
NCT06106022 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06106022 about?
NCT06106022 is a clinical study titled "A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease". The aim of this study is to evaluate the pharmacokinetic (PK) profile of vonoprazan (10 or 20 mg once daily \[QD\]) in children ≥ 6 to \< 12 years of age who have symptomatic Gastroesophageal Reflux Disease (GERD).
What is the current status of trial NCT06106022?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2023-11-01. Estimated completion is 2024-04-29.
What interventions are being tested in trial NCT06106022?
The interventions under investigation include: Vonoprazan (DRUG).
Who is sponsoring clinical trial NCT06106022?
This trial is sponsored by Phathom Pharmaceuticals, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06106022's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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