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NCT06091189 · ClinicalTrials.gov registry record · Early Phase 1
Internalized Stress in Relation to Alcohol Consumption
A Early Phase 1 study, sponsored by Texas Tech University.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 165
- Enrollment target
NCT06091189: Clinical Trial Early Phase 1 study, sponsored by Texas Tech University.
NCT06091189 is a Early Phase 1 study that was terminated before completion, run by Texas Tech University. The registered enrollment target is 165 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (211% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06091189, a Early Phase 1 study, was terminated before completion, sponsored by Texas Tech University.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 165 participants
- Enrollment target
Study Summary
The proposed study uses an experimental design to establish causal support for the role of internalized stress, pertaining to uncertainty with regard to one's sexual orientation, in contributing to heavy drinking behavior. Following exposure to internalized sexual stigma, physiological and psychological stress responses are expected to increase alcohol consumption in adults who are uncertain about their sexual orientation, especially among females, and following consumption, the physiological effects of ethanol and beliefs about the effects of alcohol are expected to alter relations between exposure to sexual stigma and the alleviation of psychological distress. Showing that physiological stress responses, whether driven by the pharmacological effects of ethanol or expectancies regarding its effects, can account for known alcohol-use disparities, particularly in bisexual/bi+ communities, would contribute a great deal to knowledge on the biology of addiction and inform subsequent interventions that seek to regulate stress reactivity.
Primary Outcome
Total beverage consumption in 35-minute tasting period.
Interventions
- DRUG Ethanol
- BEHAVIORAL Relevant Trier Social Stressor Test (TSST)
- BEHAVIORAL Placebo Trier Social Stressor Test (TSST)
- BEHAVIORAL Placebo Beverage
- BEHAVIORAL Irrelevant Trier Social Stressor Test (TSST)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2024-02-12 |
| Est. Completion | 2025-02-28 |
| Phase | Early Phase 1 |
Why NCT06091189 stopped before completion
NCT06091189 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (211% higher).
The record links to 0 conditions, and to 5 interventions - of which Ethanol is the first listed.
NCT06091189 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06091189 about?
NCT06091189 is a clinical study titled "Internalized Stress in Relation to Alcohol Consumption". The proposed study uses an experimental design to establish causal support for the role of internalized stress, pertaining to uncertainty with regard to one's sexual orientation, in contributing to heavy drinking behavior. Following exposure to internalized sexual stigma, physiological and psycholog...
What is the current status of trial NCT06091189?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 165 participants. The study started on 2024-02-12. Estimated completion is 2025-02-28.
What interventions are being tested in trial NCT06091189?
The interventions under investigation include: Ethanol (DRUG), Relevant Trier Social Stressor Test (TSST) (BEHAVIORAL), Placebo Trier Social Stressor Test (TSST) (BEHAVIORAL), Placebo Beverage (BEHAVIORAL), Irrelevant Trier Social Stressor Test (TSST) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06091189?
This trial is sponsored by Texas Tech University, which has 69 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06091189's enrollment target sits among peer trials
165 80th of 2000 higher than 1,918 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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