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NCT06080438 · ClinicalTrials.gov registry record · Phase 4
Effect of Topical Botulinum Toxin Eyedrop on Palpebral Fissure
A Phase 4 study, sponsored by University of Miami.
- Terminated
- Registry status
- Phase 4
- Development phase
- 2
- Enrollment target
NCT06080438: Clinical Trial Phase 4 study, sponsored by University of Miami.
NCT06080438 is a Phase 4 study that was terminated before completion, run by University of Miami. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06080438, a Phase 4 study, was terminated before completion, sponsored by University of Miami.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 2 participants
- Enrollment target
Study Summary
The purpose of this research study is to test if Topical (applied to the surface of the eye) Botulinum Toxin temporarily lowers the upper eyelid and makes the eyelid appear less open and thereby affects the eye surface and decreases reflexive tearing.
Primary Outcome
Palpebral fissure on Day 3 minus palpebral fissure at baseline. Palpebral fissure is the area between the upper and lower eyelid margins. Palpebral fissure height on eyes is measured in primary gaze position with a clear ruler held in a central vertical position between the upper and lower eyelid margin.
Interventions
- DRUG Botulinum toxin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2022-11-29 |
| Est. Completion | 2024-07-28 |
| Phase | Phase 4 |
Why NCT06080438 stopped before completion
NCT06080438 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Botulinum toxin is the first listed.
NCT06080438 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06080438 about?
NCT06080438 is a clinical study titled "Effect of Topical Botulinum Toxin Eyedrop on Palpebral Fissure". The purpose of this research study is to test if Topical (applied to the surface of the eye) Botulinum Toxin temporarily lowers the upper eyelid and makes the eyelid appear less open and thereby affects the eye surface and decreases reflexive tearing.
What is the current status of trial NCT06080438?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2022-11-29. Estimated completion is 2024-07-28.
What interventions are being tested in trial NCT06080438?
The interventions under investigation include: Botulinum toxin (DRUG).
Who is sponsoring clinical trial NCT06080438?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06080438's enrollment target sits among peer trials
2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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