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NCT06072378 · ClinicalTrials.gov registry record · NA
The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans
A NA study of Memory, Short-Term, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06072378: Recruiting NA study of Memory, Short-Term, sponsored by Rutgers, The State University of New Jersey.
NCT06072378 is a NA study of Memory, Short-Term that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06072378, a NA study of Memory, Short-Term, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Learning to make good decisions in the present, and accurately recalling events and information from the past, are critical aspects of human cognition that are often impaired in many psychiatric disorders. This project aims to identify the how the choices individuals make influence what, and how, people remember by combining disparate techniques in computational modeling and direct brain recordings in human subjects. The researcher developed a dual-task paradigm, probing how decisions in one task affect immediate recognition memory. To examine the neural mechanisms underlying model-free RL's influence on memory, the researcher will record local field potential (LFP) and single neuron activity in various brain regions as epilepsy patients perform the proposed task. The results of this project will identify specific neurocomputational mechanisms unifying decision-making and memory processes.
Primary Outcome
Detection of local-field potentials (LFPs) in the various regions (hippocampus, amygdala, and frontal cortex). Local field potentials are the biological voltages recorded by macroelectrodes implanted in participant's subcortical regions as part of their treatment for epilepsy. LFP changes (measured as increases or decreases in voltage) as a function of participant behavior will be recorded, and in response to the task manipulation of the value of choices during the decision-making task
Conditions Studied
Interventions
- BEHAVIORAL Value-manipulation
Study Locations (1)
New Jersey
- Rutgers Robert Wood Johnson Medical School - New Brunswick
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-10-31 |
| Est. Completion | 2028-09-01 |
| Phase | NA |
What NCT06072378 shows while recruiting
NCT06072378 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Memory, Short-Term appearing as the primary indexed condition, and to 1 intervention - of which Value-manipulation is the first listed.
NCT06072378 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT06072378 about?
NCT06072378 is a clinical study titled "The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans". Learning to make good decisions in the present, and accurately recalling events and information from the past, are critical aspects of human cognition that are often impaired in many psychiatric disorders. This project aims to identify the how the choices individuals make influence what, and how, pe...
What is the current status of trial NCT06072378?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-10-31. Estimated completion is 2028-09-01.
What conditions does trial NCT06072378 study?
This clinical trial studies the following conditions: Memory, Short-Term.
What interventions are being tested in trial NCT06072378?
The interventions under investigation include: Value-manipulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06072378?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06072378 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06072378's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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