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NCT06071442 · ClinicalTrials.gov registry record · Phase 1
Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine
A Phase 1 study, sponsored by Alexion Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
NCT06071442: Completed Phase 1 study, sponsored by Alexion Pharmaceuticals.
NCT06071442 is a Phase 1 study that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 60 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06071442, a Phase 1 study, has completed, sponsored by Alexion Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study will investigate the potential drug interactions between vemircopan and metformin, rosuvastatin, levonorgestrel/ ethinyl estradiol (LNG/EE)-containing oral contraceptive(s) (OCs), and carbamazepine in healthy participants.
Primary Outcome
Cmax for single-dose metformin without and with co-administration with vemircopan will be assessed to determine the effect of multiple doses of vemircopan on the single-dose PK of metformin.
Interventions
- DRUG Metformin
- DRUG Rosuvastatin
- DRUG Carbamazepine
- DRUG Vemircopan
- DRUG Levonorgestrel / Ethinyl Estradiol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-01-17 |
| Est. Completion | 2024-04-12 |
| Phase | Phase 1 |
What the finished NCT06071442 record still lists
NCT06071442 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 5 interventions - of which Metformin is the first listed.
NCT06071442 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06071442 about?
NCT06071442 is a clinical study titled "Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine". This study will investigate the potential drug interactions between vemircopan and metformin, rosuvastatin, levonorgestrel/ ethinyl estradiol (LNG/EE)-containing oral contraceptive(s) (OCs), and carbamazepine in healthy participants.
What is the current status of trial NCT06071442?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2024-01-17. Estimated completion is 2024-04-12.
What interventions are being tested in trial NCT06071442?
The interventions under investigation include: Metformin (DRUG), Rosuvastatin (DRUG), Carbamazepine (DRUG), Vemircopan (DRUG), Levonorgestrel / Ethinyl Estradiol (DRUG).
Who is sponsoring clinical trial NCT06071442?
This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06071442's enrollment target sits among peer trials
60 831st of 2000 higher than 1,106 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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