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NCT06063174 · ClinicalTrials.gov registry record · NA
Stress & Resilience Study
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 712
- Enrollment target
NCT06063174: Completed NA study, sponsored by University of California, Los Angeles.
NCT06063174 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 712 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (49% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06063174, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 712 participants
- Enrollment target
Study Summary
Goal 1: The investigators will quantify lifetime stress burden and examine mechanisms linking Adverse Childhood Experiences (ACEs) and health. The investigators will quantify the early life and total lifetime stress burden of a representative sample of about 725 adults (aged 18+) across northern and southern California. In addition, the investigators will examine how prior life stress exposure and current stress levels are associated with differences in psychosocial, immune, metabolic, physiologic, and clinical outcomes for all participants at baseline. Goal 2: The investigators will develop and test a biopsychosocial intervention using existing programs, platforms, resources, and core components from trauma and resilience research that will target five stress-related domains (i.e., cognitive response style, social relationships, eating, sleep, and physical activity) using cognitive restructuring and mindfulness, interpersonal skills training, mindful eating training, sleep training, and behavioral activation/mobility training. The investigators will then assess the efficacy and acceptability of the intervention in about 425 high stress exposure participants from Goal 1. Following their baseline assessment, about 425 participants will be randomly assigned to receive for 12 weeks (a) personalized intervention, (b) environmental education (active control) or (c) nothing (non-active control). The investigators will also assess the efficacy of the personalized intervention by comparing changes in outcomes by condition from baseline (prior to randomization) to immediately after the intervention, and then again after 12 weeks following intervention completion. The interventions will be entirely online/remote.
Primary Outcome
The primary endpoint will be the change in Perceived Stress Scale (PSS-10) score between the nonactive control, active control, and the treatment groups (combined) from screening to Follow-up 1 \& 2. A meaningful clinically significant score in the PSS-10 score is a difference of 5 points. The range of the PSS-10 is 0-40, with higher scores indicating more perceived stress. As such PSS-10 change scores could range from -40 to 40. A positive PSS-10 change score indicates increased stress and is a
Interventions
- BEHAVIORAL Education Program
- BEHAVIORAL Think Well Program
- BEHAVIORAL Be Well Program
- BEHAVIORAL Eat Well Program
- BEHAVIORAL Sleep Well Program
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 712 participants |
| Start Date | 2023-06-30 |
| Est. Completion | 2024-10-30 |
| Phase | NA |
What the finished NCT06063174 record still lists
NCT06063174 is an interventional study that assigns participants to a tested intervention. The registered 712 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (49% lower).
The record links to 0 conditions, and to 5 interventions - of which Education Program is the first listed.
NCT06063174 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06063174 about?
NCT06063174 is a clinical study titled "Stress & Resilience Study". Goal 1: The investigators will quantify lifetime stress burden and examine mechanisms linking Adverse Childhood Experiences (ACEs) and health. The investigators will quantify the early life and total lifetime stress burden of a representative sample of about 725 adults (aged 18+) across northern and...
What is the current status of trial NCT06063174?
This trial is currently completed. It is a NA study. The enrollment target is 712 participants. The study started on 2023-06-30. Estimated completion is 2024-10-30.
What interventions are being tested in trial NCT06063174?
The interventions under investigation include: Education Program (BEHAVIORAL), Think Well Program (BEHAVIORAL), Be Well Program (BEHAVIORAL), Eat Well Program (BEHAVIORAL), Sleep Well Program (BEHAVIORAL).
Who is sponsoring clinical trial NCT06063174?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06063174's enrollment target sits among peer trials
712 147th of 2000 higher than 1,854 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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