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NCT06057675 · ClinicalTrials.gov registry record · Phase 2

Tranexamic Acid in Nasal Mohs Reconstruction

A Phase 2 study of Skin Cancer Face and Postoperative Bleeding, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
Phase 2
Development phase
100
Enrollment target
1
Study location

NCT06057675: Recruiting Phase 2 study of Skin Cancer Face and Postoperative Bleeding, sponsored by Vanderbilt University Medical Center.

NCT06057675 is a Phase 2 study of Skin Cancer Face and Postoperative Bleeding that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06057675, a Phase 2 study of Skin Cancer Face and Postoperative Bleeding, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.

Primary Outcome

Photos will be taken by a research team member at the first postoperative clinic visit and then analyzed and graded by a blinded reviewer for measures including surgical site bruising and swelling. Surgical site swelling and bruising will be graded on a 4 point scale, with 0 indicating no swelling and bruising and 3 indicating significant swelling and bruising.

Interventions

  • DRUG Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine)
  • DRUG Control (1% lidocaine with 1:100,000 epinephrine)

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2024-03-19
Est. Completion 2026-06
Phase Phase 2

What NCT06057675 shows while recruiting

NCT06057675 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).

The record links to 2 conditions, with Skin Cancer Face appearing as the primary indexed condition, and to 2 interventions - of which Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine) is the first listed.

NCT06057675 reports a single indexed study location in Tennessee.

Frequently Asked Questions

What is clinical trial NCT06057675 about?

NCT06057675 is a clinical study titled "Tranexamic Acid in Nasal Mohs Reconstruction". This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.

What is the current status of trial NCT06057675?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2024-03-19. Estimated completion is 2026-06.

What conditions does trial NCT06057675 study?

This clinical trial studies the following conditions: Skin Cancer Face, Postoperative Bleeding.

What interventions are being tested in trial NCT06057675?

The interventions under investigation include: Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine) (DRUG), Control (1% lidocaine with 1:100,000 epinephrine) (DRUG).

Who is sponsoring clinical trial NCT06057675?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06057675 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Skin Cancer Face

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06057675's enrollment target sits among peer trials

100 672nd of 2000 higher than 1,264 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06057675, the US trial registry maintained by the National Library of Medicine. NCT06057675 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.