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NCT06048809 · ClinicalTrials.gov registry record · NA
A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome
A NA study, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT06048809: Completed NA study, sponsored by HALEON.
NCT06048809 is a NA study that has completed, run by HALEON. The registered enrollment target is 56 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06048809, a NA study, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
The aim of this study is to evaluate the effect of a toothpaste containing stannous fluoride (SnF2) over time on the oral bacterial composition and activity and to explore its effect in comparison to a regular fluoride toothpaste.
Primary Outcome
Alpha diversity was defined as species diversity in sites or habitats and was used to describe the overall oral bacterial composition. Samples were collected from 4 different areas of mouth (tongue, supragingival plaque, subgingival surface, and saliva) and microbial profiling (16S ribosomal ribonucleic acid \[rRNA\] gene amplicon analysis) was performed to identify the bacteria present within a given sample down to the genus and/or species level. Alpha diversity (overall) was measured using Sha
Interventions
- OTHER Stannous Fluoride Toothpaste (Sensodyne Repair and Protect)
- OTHER Regular Fluoride Toothpaste (Colgate Cavity Protection)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2024-04-10 |
| Est. Completion | 2024-05-30 |
| Phase | NA |
What the finished NCT06048809 record still lists
NCT06048809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Stannous Fluoride Toothpaste (Sensodyne Repair and Protect) is the first listed.
NCT06048809 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06048809 about?
NCT06048809 is a clinical study titled "A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome". The aim of this study is to evaluate the effect of a toothpaste containing stannous fluoride (SnF2) over time on the oral bacterial composition and activity and to explore its effect in comparison to a regular fluoride toothpaste.
What is the current status of trial NCT06048809?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2024-04-10. Estimated completion is 2024-05-30.
What interventions are being tested in trial NCT06048809?
The interventions under investigation include: Stannous Fluoride Toothpaste (Sensodyne Repair and Protect) (OTHER), Regular Fluoride Toothpaste (Colgate Cavity Protection) (OTHER).
Who is sponsoring clinical trial NCT06048809?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06048809's enrollment target sits among peer trials
56 1262nd of 2000 higher than 737 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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