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NCT06047366 · ClinicalTrials.gov registry record · Phase 4
Combination of Buffered Anesthetic to Treat Mandibular Molars
A Phase 4 study, sponsored by Indiana University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
NCT06047366: Clinical Trial Phase 4 study, sponsored by Indiana University.
NCT06047366 is a Phase 4 study that was terminated before completion, run by Indiana University. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06047366, a Phase 4 study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether a combination of anesthetics (numbing medicine) will adequately anesthetize teeth over a different combination. A second purpose is to see if the time needed to numb the nerve in a tooth is different between the two anesthetics.
Primary Outcome
Patient will report their comfort during treatment based on a visual analogue scale (VAS) graphic. Visual analog scale (VAS) is based on a scale of 0-10 related to patient comfort. A VAS score of 10 would mean the patient was extremely uncomfortable during treatment indicating there was inadequate anesthesia. A VAS score of 0 indicates no pain.
Interventions
- DRUG Sodium bicarbonate
- DRUG Lidocaine w/ epi
- DRUG Articaine w/ epi
- DRUG Mepivacaine plain
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-12-05 |
| Est. Completion | 2024-05-15 |
| Phase | Phase 4 |
Why NCT06047366 stopped before completion
NCT06047366 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 4 interventions - of which Sodium bicarbonate is the first listed.
NCT06047366 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06047366 about?
NCT06047366 is a clinical study titled "Combination of Buffered Anesthetic to Treat Mandibular Molars". The purpose of this study is to determine whether a combination of anesthetics (numbing medicine) will adequately anesthetize teeth over a different combination. A second purpose is to see if the time needed to numb the nerve in a tooth is different between the two anesthetics.
What is the current status of trial NCT06047366?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2023-12-05. Estimated completion is 2024-05-15.
What interventions are being tested in trial NCT06047366?
The interventions under investigation include: Sodium bicarbonate (DRUG), Lidocaine w/ epi (DRUG), Articaine w/ epi (DRUG), Mepivacaine plain (DRUG).
Who is sponsoring clinical trial NCT06047366?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06047366's enrollment target sits among peer trials
40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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