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NCT06044740 · ClinicalTrials.gov registry record · Early Phase 1
Sevoflurane's Effect on Neurocognition Study
A Early Phase 1 study, sponsored by Keith M Vogt.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 42
- Enrollment target
NCT06044740: Completed Early Phase 1 study, sponsored by Keith M Vogt.
NCT06044740 is a Early Phase 1 study that has completed, run by Keith M Vogt. The registered enrollment target is 42 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (21% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06044740, a Early Phase 1 study, has completed, sponsored by Keith M Vogt.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose sevoflurane. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will occur over 2 visits and involves no long-term follow up.
Primary Outcome
Event-related blood-oxygen level dependent (BOLD) Magnetic Resonance Imaging (MRI) responses will be determined for each experimental item presented, revealing localized changes in blood flow, which correlate to increased neuronal activity. These will be averaged across the multiple repetitions of each type of experimental item (memory only, pain only, and memory+pain), creating an anatomical map of Z-scores. Cross-condition comparisons will be the main effect of interest, comparing no sevoflura
Interventions
- DRUG Sevoflurane
- DEVICE Peripheral Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2024-01-17 |
| Est. Completion | 2026-01-30 |
| Phase | Early Phase 1 |
What the finished NCT06044740 record still lists
NCT06044740 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (21% lower).
The record links to 0 conditions, and to 2 interventions - of which Sevoflurane is the first listed.
NCT06044740 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06044740 about?
NCT06044740 is a clinical study titled "Sevoflurane's Effect on Neurocognition Study". The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose sevoflurane. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will o...
What is the current status of trial NCT06044740?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 42 participants. The study started on 2024-01-17. Estimated completion is 2026-01-30.
What interventions are being tested in trial NCT06044740?
The interventions under investigation include: Sevoflurane (DRUG), Peripheral Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT06044740?
This trial is sponsored by Keith M Vogt, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06044740's enrollment target sits among peer trials
42 605th of 2000 higher than 1,379 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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