Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06043414 · ClinicalTrials.gov registry record · NA
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
A NA study, sponsored by University of Southern California.
- Not yet
- Registry status
- NA
- Development phase
- 250
- Enrollment target
NCT06043414 is a NA study that has not yet begun recruiting, run by University of Southern California. The registered enrollment target is 250 participants.
The verdict
NCT06043414, a NA study, has not yet begun recruiting, sponsored by University of Southern California.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
Study Summary
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory laparotomy. The study addresses the common complications of incisional surgical site infections (SSI) and fascial dehiscence (FD) following emergency exploratory laparotomy. The primary objective is to assess the effectiveness of triclosan-coated barbed suture and conventional non-barbed suture in reducing the rates of incisional SSI and FD within 30 days postoperatively. The study population comprises adult patients undergoing emergent laparotomy for traumatic injuries or acute intraabdominal pathology. This prospective, single-blinded randomized control trial will be conducted at Los Angeles General Medical Center. Patients will be randomized to receive either triclosan-coated barbed suture or conventional non-barbed suture for abdominal fascial closure, with a standard closure technique employed. Patients will be followed up for 30 days postoperatively to monitor surgical site infections, fascial dehiscence, and other outcomes. Statistical analysis will be conducted to compare outcomes between the study arms, assessing the efficacy of triclosan-coated barbed suture in reducing the incidence of SSI and FD, along with secondary outcomes.
Interventions
- DEVICE triclosan-coated barbed suture
- DEVICE triclosan-coated non-barbed suture
- DEVICE Non-coated non-barbed suture
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2024-01-01 |
| Est. Completion | 2027-01-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06043414
The ClinicalTrials.gov registry entry for NCT06043414 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which triclosan-coated barbed suture is the first listed.
NCT06043414 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06043414 about?
NCT06043414 is a clinical study titled "Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT". This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory laparotomy. The study addresses the common complications of incisional surgi...
What is the current status of trial NCT06043414?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2024-01-01. Estimated completion is 2027-01-31.
What interventions are being tested in trial NCT06043414?
The interventions under investigation include: triclosan-coated barbed suture (DEVICE), triclosan-coated non-barbed suture (DEVICE), Non-coated non-barbed suture (DEVICE).
Who is sponsoring clinical trial NCT06043414?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.