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NCT06041386 · ClinicalTrials.gov registry record · Phase 4
REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study
A Phase 4 study of Asthma, sponsored by GlaxoSmithKline.
- Active
- Registry status
- Phase 4
- Development phase
- 336
- Enrollment target
- 20
- Study locations
NCT06041386: Active Phase 4 study of Asthma, sponsored by GlaxoSmithKline.
NCT06041386 is a Phase 4 study of Asthma that is active but no longer recruiting, run by GlaxoSmithKline. The registered enrollment target is 336 participants, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (78% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06041386, a Phase 4 study of Asthma, is active but no longer recruiting, sponsored by GlaxoSmithKline.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 336 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an eosinophilic phenotype (SA-EP).
Primary Outcome
4-component clinical remission is defined as (a) No clinically significant asthma exacerbations (b) No OCS use for asthma (c) Well controlled asthma based on an Asthma Control Test (ACT) (d) No clinically significant deterioration of lung function.
Conditions Studied
Interventions
- DRUG Mepolizumab
- OTHER Spirometry
Study Locations (20)
Florida
- GSK Investigational Site - Homestead
- GSK Investigational Site - Jacksonville
- GSK Investigational Site - Miami
- GSK Investigational Site - Plantation
California
- GSK Investigational Site - La Jolla
- GSK Investigational Site - Newport Beach
Colorado
- GSK Investigational Site - Aurora
- GSK Investigational Site - Colorado Springs
Georgia
- GSK Investigational Site - Adairsville
- GSK Investigational Site - Columbus
Kentucky
- GSK Investigational Site - Lexington
- GSK Investigational Site - Owensboro
Maryland
- GSK Investigational Site - Glenn Dale
- GSK Investigational Site - Towson
Connecticut
- GSK Investigational Site - New Haven
Louisiana
- GSK Investigational Site - New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 336 participants |
| Start Date | 2024-03-20 |
| Est. Completion | 2028-06-14 |
| Phase | Phase 4 |
What the registry record for NCT06041386 still lists
NCT06041386 is an interventional study that assigns participants to a tested intervention. The registered 336 participants enrollment target is mid-sized for trials with a published cap, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which Mepolizumab is the first listed.
NCT06041386 names 20 study sites across 12 states, led by Florida, California, Colorado.
Frequently Asked Questions
What is clinical trial NCT06041386 about?
NCT06041386 is a clinical study titled "REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study". This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an eosinophilic phenotype (SA-EP).
What is the current status of trial NCT06041386?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 336 participants. The study started on 2024-03-20. Estimated completion is 2028-06-14.
What conditions does trial NCT06041386 study?
This clinical trial studies the following conditions: Asthma.
What interventions are being tested in trial NCT06041386?
The interventions under investigation include: Mepolizumab (DRUG), Spirometry (OTHER).
Who is sponsoring clinical trial NCT06041386?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06041386 being conducted?
This trial has 20 study locations across California, Colorado, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06041386's enrollment target sits among peer trials
336 113th of 374 higher than 261 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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