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ACTIVE NOT RECRUITING Phase 4

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study

NCT06041386 · View on ClinicalTrials.gov ↗

Study Summary

This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an eosinophilic phenotype (SA-EP).

Conditions Studied

Interventions

  • DRUG Mepolizumab
  • OTHER Spirometry

Study Locations (20)

Florida

  • GSK Investigational Site — Homestead
  • GSK Investigational Site — Jacksonville
  • GSK Investigational Site — Miami
  • GSK Investigational Site — Plantation

California

  • GSK Investigational Site — La Jolla
  • GSK Investigational Site — Newport Beach

Colorado

  • GSK Investigational Site — Aurora
  • GSK Investigational Site — Colorado Springs

Georgia

  • GSK Investigational Site — Adairsville
  • GSK Investigational Site — Columbus

Kentucky

  • GSK Investigational Site — Lexington
  • GSK Investigational Site — Owensboro

Maryland

  • GSK Investigational Site — Glenn Dale
  • GSK Investigational Site — Towson

Connecticut

  • GSK Investigational Site — New Haven

Louisiana

  • GSK Investigational Site — New Orleans

Trial Details

FieldValue
Enrollment Target 336 participants
Start Date 2024-03-20
Est. Completion 2028-06-14
Phase Phase 4

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06041386

The ClinicalTrials.gov registry entry for NCT06041386 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 336 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 2 interventions — of which Mepolizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06041386 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06041386 about?

NCT06041386 is a clinical study titled "REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study". This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an eosinophilic phenotype (SA-EP).

What is the current status of trial NCT06041386?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 336 participants. The study started on 2024-03-20. Estimated completion is 2028-06-14.

What conditions does trial NCT06041386 study?

This clinical trial studies the following conditions: Asthma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06041386?

The interventions under investigation include: Mepolizumab (DRUG), Spirometry (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06041386?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06041386 being conducted?

This trial has 20 study locations across California, Colorado, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial