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NCT06041048 · ClinicalTrials.gov registry record · Phase 4
Investigation of Locus Coeruleus Function in Sustained Attention
A Phase 4 study of Attention - no Condition is Being Assessed - Healthy Adults, sponsored by University of California, Davis.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT06041048 is a Phase 4 study of Attention - no Condition is Being Assessed - Healthy Adults that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06041048, a Phase 4 study of Attention - no Condition is Being Assessed - Healthy Adults, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has been implicated in dysfunctions including attention deficit hyperactivity disorder and schizophrenia. The goal of this proposal is to develop methods that permit measurement of activity in the human LC. Because the LC is small and located in the pons, the Investigators will use high resolution magnetic resonance imaging techniques tailored to the brainstem environment, including neuromelanin-sensitive images shown to delineate the LC, combined with pharmacological manipulation to confirm the location of functional activity.
Conditions Studied
Interventions
- DRUG Modafinil
Study Locations (1)
California
- University of California, Davis - Sacramento
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-10-01 |
| Est. Completion | 2025-12-30 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06041048
The ClinicalTrials.gov registry entry for NCT06041048 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Attention - no Condition is Being Assessed - Healthy Adults appearing as the primary indexed condition, and to 1 intervention - of which Modafinil is the first listed.
NCT06041048 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06041048 about?
NCT06041048 is a clinical study titled "Investigation of Locus Coeruleus Function in Sustained Attention". The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has been implicated in dysfunctions including attention deficit hyperactivity disorder and schizophrenia. The goal of this proposal is to develop me...
What is the current status of trial NCT06041048?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2023-10-01. Estimated completion is 2025-12-30.
What conditions does trial NCT06041048 study?
This clinical trial studies the following conditions: Attention - no Condition is Being Assessed - Healthy Adults.
What interventions are being tested in trial NCT06041048?
The interventions under investigation include: Modafinil (DRUG).
Who is sponsoring clinical trial NCT06041048?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06041048 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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