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NCT06029452 · ClinicalTrials.gov registry record
A Retrospective Validation Study To Identify Chart-Based Clinical Diagnosis Of Wild-Type Transthyretin Amyloid Cardiomyopathy (Attrwt-CM) And Non-Amyloid Heart Failure Among Patients With Heart Failure (HF).
A clinical trial, sponsored by Pfizer.
- Completed
- Registry status
- 558
- Enrollment target
NCT06029452: Completed study, sponsored by Pfizer.
NCT06029452 is a clinical trial that has completed, run by Pfizer. The registered enrollment target is 558 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06029452 has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- 558 participants
- Enrollment target
Study Summary
This is an observational, retrospective non-inferiority study with a study sample from a large national database. A machine learning (ML) model will use a national database to predict the clinical diagnosis of ATTRwt-CM among HF patients. This study will include HF patients ≥50 years old.
Primary Outcome
In this outcome measure number of participants were reported according to clinical diagnosis predicted by ML algorithm. True positive (TP) = participants with actual and predicted diagnosis of ATTRwt-CM; False positive (FP) = participants with actual diagnosis of non-amyloid HF and predicted diagnosis of ATTRwt-CM; False negative (FN) = participants with actual diagnosis of ATTRwt-CM and predicted diagnosis of non-amyloid HF; True negative (TN) = participants with actual and predicted diagnosis
Interventions
- OTHER Machine learning algorithm
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 558 participants |
| Start Date | 2023-09-01 |
| Est. Completion | 2023-11-14 |
What the finished NCT06029452 record still lists
NCT06029452 is an observational study that tracks outcomes without assigning an intervention. The registered 558 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Machine learning algorithm is the first listed.
NCT06029452 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06029452 about?
NCT06029452 is a clinical study titled "A Retrospective Validation Study To Identify Chart-Based Clinical Diagnosis Of Wild-Type Transthyretin Amyloid Cardiomyopathy (Attrwt-CM) And Non-Amyloid Heart Failure Among Patients With Heart Failure (HF).". This is an observational, retrospective non-inferiority study with a study sample from a large national database. A machine learning (ML) model will use a national database to predict the clinical diagnosis of ATTRwt-CM among HF patients. This study will include HF patients ≥50 years old.
What is the current status of trial NCT06029452?
This trial is currently completed. The enrollment target is 558 participants. The study started on 2023-09-01. Estimated completion is 2023-11-14.
What interventions are being tested in trial NCT06029452?
The interventions under investigation include: Machine learning algorithm (OTHER).
Who is sponsoring clinical trial NCT06029452?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
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