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NCT06017986 · ClinicalTrials.gov registry record · NA
The Effect of Processing on Food Reward
A NA study of Metabolic Diseases, sponsored by Virginia Polytechnic Institute and State University.
- Recruiting
- Registry status
- NA
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT06017986 is a NA study of Metabolic Diseases that is actively recruiting participants, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 74 participants, below the 192-participant average among 12 other Metabolic Diseases trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06017986, a NA study of Metabolic Diseases, is actively recruiting participants, sponsored by Virginia Polytechnic Institute and State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
The minimally processed diets of our ancestors have been rapidly replaced by UPFs driving poor diet to become the leading risk factor for preventable death globally. Hence, it is essential to understand what properties of UPF are driving their overconsumption to reduce diet-related mortality. To address this gap in knowledge this proposal will test: * If UPFs have a greater post meal metabolic response when compared to MPFs an essential signal for food reward * Through the use of an auction task paradigm if UPFs overvalued and if this value is differentially encoded in the brain This study is a fully cross-over design in that each participant receives all conditions and therefore serves as their own control. All orders of foods will be counterbalanced. Although participants cannot be blinded to the conditions as they must be aware of the foods they are eating, they will not be made aware that the key manipulation is food processing. On different days participants will come to the lab and consume a meal containing either minimally or ultra-processed foods as determined by the widely used NOVA (not an acronym) scale. These conditions will be consumed in a whole room metabolic chamber allowing for simultaneous measurement of multiple metabolic responses (glucose, insulin, and metabolic rate). These measures will be collected for 45 min before consumption of the meal (baseline) and for 3 hours after consumption (post-prandial). All participants will also undergo a Becker-Degroot-Marschak auction paradigm that consists of foods that are either minimally or Ultra-processed in the MRI scanner. Food value will be measure in participants' willingness to pay for each food and Neural responses will be measured during presentation of the food cues.
Conditions Studied
Interventions
- OTHER Ultra-processed food - Picture Set Meal
- OTHER Ultra-processed food - Additives Meal
- OTHER Ultra-processed food - Ingredients Meal
- OTHER Minimally Processed Food - Picture Set Meal
- OTHER Minimally Processed Food - Additives Meal
Study Locations (1)
Virginia
- Fralin Biomedical Research Institute at VTC - Roanoke
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2023-07-01 |
| Est. Completion | 2026-07-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06017986
The ClinicalTrials.gov registry entry for NCT06017986 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 192-participant average among 12 other Metabolic Diseases trials with a reported enrollment target (61% lower). The listed sponsor is Virginia Polytechnic Institute and State University, which has 104 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Metabolic Diseases appearing as the primary indexed condition, and to 5 interventions - of which Ultra-processed food - Picture Set Meal is the first listed.
NCT06017986 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT06017986 about?
NCT06017986 is a clinical study titled "The Effect of Processing on Food Reward". The minimally processed diets of our ancestors have been rapidly replaced by UPFs driving poor diet to become the leading risk factor for preventable death globally. Hence, it is essential to understand what properties of UPF are driving their overconsumption to reduce diet-related mortality. To add...
What is the current status of trial NCT06017986?
This trial is currently recruiting. It is a NA study. The enrollment target is 74 participants. The study started on 2023-07-01. Estimated completion is 2026-07-01.
What conditions does trial NCT06017986 study?
This clinical trial studies the following conditions: Metabolic Diseases.
What interventions are being tested in trial NCT06017986?
The interventions under investigation include: Ultra-processed food - Picture Set Meal (OTHER), Ultra-processed food - Additives Meal (OTHER), Ultra-processed food - Ingredients Meal (OTHER), Minimally Processed Food - Picture Set Meal (OTHER), Minimally Processed Food - Additives Meal (OTHER).
Who is sponsoring clinical trial NCT06017986?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06017986 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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