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NCT06016764 · ClinicalTrials.gov registry record · Phase 1
Use of MRI and cTBS for Catatonia in Autism
A Phase 1 study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 26
- Enrollment target
NCT06016764: Completed Phase 1 study, sponsored by Vanderbilt University Medical Center.
NCT06016764 is a Phase 1 study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06016764, a Phase 1 study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
Despite the significant morbidity and mortality associated with catatonia in autism, no diagnostic research has attempted to identify biomarkers for catatonia. This application will use a participant's own individual brain magnetic resonance image to target the primary motor strip with transcranial magnetic stimulation; to determine if hyper-excitability of the brain directly correlates with symptoms of catatonia and social-emotional impairment in autism. Completion of this project would result in the first study to associate hyper-excitability of the brain with catatonia and core features of autism; findings which are likely to have a significant impact on the health and well-being of autistic individuals.
Primary Outcome
Three batches of 10 MEPs will be recorded before cTBS and used as a baseline measure of motor evoked potentials.
Interventions
- DEVICE Continuous Theta Burst in Transcranial Magnetic Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2023-08-23 |
| Est. Completion | 2025-12-01 |
| Phase | Phase 1 |
What the finished NCT06016764 record still lists
NCT06016764 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 1 intervention - of which Continuous Theta Burst in Transcranial Magnetic Stimulation is the first listed.
NCT06016764 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06016764 about?
NCT06016764 is a clinical study titled "Use of MRI and cTBS for Catatonia in Autism". Despite the significant morbidity and mortality associated with catatonia in autism, no diagnostic research has attempted to identify biomarkers for catatonia. This application will use a participant's own individual brain magnetic resonance image to target the primary motor strip with transcranial ...
What is the current status of trial NCT06016764?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2023-08-23. Estimated completion is 2025-12-01.
What interventions are being tested in trial NCT06016764?
The interventions under investigation include: Continuous Theta Burst in Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT06016764?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06016764's enrollment target sits among peer trials
26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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