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NCT06015490 · ClinicalTrials.gov registry record · NA

The Impact of the Physiological Response to Sugar on Brain Activity and Behavior

A NA study, sponsored by Virginia Polytechnic Institute and State University.

Completed
Registry status
NA
Development phase
7
Enrollment target

NCT06015490: Completed NA study, sponsored by Virginia Polytechnic Institute and State University.

NCT06015490 is a NA study that has completed, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06015490, a NA study, has completed, sponsored by Virginia Polytechnic Institute and State University.

COMPLETED
Registry status
NA
Development phase
7 participants
Enrollment target

Study Summary

The goal of this pilot study is to test the feasibility of assessing how biological factors and chemical properties of sugars may influence metabolism and food reward in humans. The main questions it aims to answer are: • Can differences in appetitive responses and neural activations to sucrose (table sugar) and its chemical components (glucose and fructose) be measured and quantified? This study is a crossover design, meaning every participant will complete every condition. Participants will consume beverages containing sucrose, glucose, or fructose, which are each novelly flavored, 6 times within a week. During one of the consumption times, energy expenditure, carbohydrate oxidation, and blood glucose will be measured in the lab before and for 2 hours after consumption. After participants have consumed each condition, they will undergo a tasting task in the MRI scanner, neural responses to receipt of the beverages are measured.

Primary Outcome

Subjective ratings of liking of flavors used in the intervention will be assessed at baseline and after the intervention. The generalized Labeled Magnitude Scale will be used. The scale is anchored by descriptors of "Most Disliked Sensation Imaginable" and "Most Liked Sensation Imaginable" at the lower and upper ends, respectively. The score is determined by the place on the scale participants select (range of scale is 0-100). An increase in score from baseline to post-intervention indicates an

Interventions

  • OTHER Glucose drink
  • OTHER Sucrose drink
  • OTHER Fructose drink

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2023-09-01
Est. Completion 2024-07-22
Phase NA

What the finished NCT06015490 record still lists

NCT06015490 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 3 interventions - of which Glucose drink is the first listed.

NCT06015490 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06015490 about?

NCT06015490 is a clinical study titled "The Impact of the Physiological Response to Sugar on Brain Activity and Behavior". The goal of this pilot study is to test the feasibility of assessing how biological factors and chemical properties of sugars may influence metabolism and food reward in humans. The main questions it aims to answer are: • Can differences in appetitive responses and neural activations to sucrose (ta...

What is the current status of trial NCT06015490?

This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2023-09-01. Estimated completion is 2024-07-22.

What interventions are being tested in trial NCT06015490?

The interventions under investigation include: Glucose drink (OTHER), Sucrose drink (OTHER), Fructose drink (OTHER).

Who is sponsoring clinical trial NCT06015490?

This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06015490's enrollment target sits among peer trials

7 1982nd of 2000 higher than 18 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06015490, the US trial registry maintained by the National Library of Medicine. NCT06015490 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.