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NCT06006585 · ClinicalTrials.gov registry record · Phase 1

A Study to Test How Well Different Doses of BI 771716 Are Tolerated by People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

A Phase 1 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT06006585: Completed Phase 1 study, sponsored by Boehringer Ingelheim.

NCT06006585 is a Phase 1 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06006585, a Phase 1 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This study is open to adults with geographic atrophy, an advanced form of age-related macular degeneration. People can join the study if they are at least 50 years old. The purpose of this study is to find out how well different doses of a medicine called BI 771716 are tolerated. This study has 2 parts. Part 1 of the study takes about 3 months. In this part, participants receive 1 injection of BI 771716 directly into one of the eyes affected by geographic atrophy. Part 2 of the study takes about 4 months. In this part, participants receive 2 injections of BI 771716 directly into the eye. There are 4 weeks between the first and the second injection. In this study, BI 771716 is given to humans for the first time. The doctors compare how well participants tolerate the different doses of BI 771716. The doctors also regularly check the general health of the participants.

Primary Outcome

SRD part

Interventions

  • DRUG BI 771716

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2023-10-06
Est. Completion 2024-05-24
Phase Phase 1
Boehringer Ingelheim

515 total trials

What the finished NCT06006585 record still lists

NCT06006585 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 1 intervention - of which BI 771716 is the first listed.

NCT06006585 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06006585 about?

NCT06006585 is a clinical study titled "A Study to Test How Well Different Doses of BI 771716 Are Tolerated by People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy". This study is open to adults with geographic atrophy, an advanced form of age-related macular degeneration. People can join the study if they are at least 50 years old. The purpose of this study is to find out how well different doses of a medicine called BI 771716 are tolerated. This study has 2 p...

What is the current status of trial NCT06006585?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2023-10-06. Estimated completion is 2024-05-24.

What interventions are being tested in trial NCT06006585?

The interventions under investigation include: BI 771716 (DRUG).

Who is sponsoring clinical trial NCT06006585?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06006585's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06006585, the US trial registry maintained by the National Library of Medicine. NCT06006585 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.