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Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection
NCT06004739 · View on ClinicalTrials.gov ↗
Study Summary
Delirium is an acute confusional state that is experienced by many older adults who are admitted to hospital. To treat delirium the underlying cause needs to be identified promptly, but this is challenging. One of the potential causes of delirium is infection. Urine tests show that most patients experiencing delirium have bacteria in their urine, however, bacteria in the urine is common among older adults, and does not automatically indicate an infection is present. As a result it is difficult to know whether a lower urinary tract infection is present as individuals with delirium are frequently unable to report clinical signs of infection - symptoms of pain or discomfort with urination, having to urinate more frequently or pelvic discomfort. Very often, individuals with delirium are treated with antibiotics despite the fact that it is unknown whether antibiotics help to improve delirium in cases where bacteria in the urine is present. This proposed study is a randomized controlled trial that will examine if adults (age 60 or older) with delirium and suspected infection benefit from taking antibiotics.
Conditions Studied
Interventions
- DRUG Start Antibiotics / Continue Antibiotics for treatment of bacteriuria
- OTHER No Antibiotics for treatment of bacteriuria
Study Locations (7)
Other
- The Ottawa Hospital Civic Campus — Ottawa
- The Ottawa Hospital General Campus — Ottawa
- Hennick Bridgepoint Hospital — Toronto
- Michael Garron Hospital — Toronto
- Mount Sinai Hospital — Toronto
- Toronto General Hospital — Toronto
Illinois
- Northwestern Memorial Hospital — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2024-05-18 |
| Est. Completion | 2027-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06004739
The ClinicalTrials.gov registry entry for NCT06004739 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 550 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mount Sinai Hospital, Canada, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Infectious Disease appearing as the primary indexed condition, and to 2 interventions — of which Start Antibiotics / Continue Antibiotics for treatment of bacteriuria is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06004739 reports 7 study locations spanning 2 distinct geographic areas — top geographies include Other, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06004739 about?
NCT06004739 is a clinical study titled "Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection". Delirium is an acute confusional state that is experienced by many older adults who are admitted to hospital. To treat delirium the underlying cause needs to be identified promptly, but this is challenging. One of the potential causes of delirium is infection. Urine tests show that most patients exp...
What is the current status of trial NCT06004739?
This trial is currently recruiting. It is a NA study. The enrollment target is 550 participants. The study started on 2024-05-18. Estimated completion is 2027-09.
What conditions does trial NCT06004739 study?
This clinical trial studies the following conditions: Infectious Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06004739?
The interventions under investigation include: Start Antibiotics / Continue Antibiotics for treatment of bacteriuria (DRUG), No Antibiotics for treatment of bacteriuria (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06004739?
This trial is sponsored by Mount Sinai Hospital, Canada, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06004739 being conducted?
This trial has 7 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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