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NCT05988619 · ClinicalTrials.gov registry record · NA
iCBT With TMS in Patients With MDD
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT05988619: Completed NA study, sponsored by University of California, Los Angeles.
NCT05988619 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05988619, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Major Depressive Disorder (MDD) is a common mental health diagnosis. While there are many approaches to the treatment of MDD, current treatments of MDD often do not substantially reduce depressive symptoms among those in need of care. Prior research suggests that combining cognitive-behavioral therapy (CBT) and psychopharmacology can produce optimal treatment outcomes compared to the use of either treatment individually. Transcranial Magnetic Stimulation (TMS) is one promising brain stimulation approach used to treat MDD, especially among patients with treatment-resistant symptoms. Like psychopharmacological interventions, TMS may produce optimal treatment outcomes when paired with CBT. However, standard TMS protocols are time-intensive, typically requiring daily doctor visits for one hour of six to eight weeks. Therefore, an internet-delivered CBT protocol may augment the effects of TMS without substantially increasing patient burden. To that end, the present study assesses if a combined TMS and internet-delivered CBT protocol may produce superior treatment outcomes compared with TMS alone.
Primary Outcome
Change in Depression Symptoms (Range = 0-52, higher indicates greater symptoms)
Interventions
- BEHAVIORAL Psychoeducation
- DEVICE Transcranial Magnetic Stimulation
- BEHAVIORAL Internet-Based Cognitive Behavioral Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-03-21 |
| Est. Completion | 2024-09-07 |
| Phase | NA |
What the finished NCT05988619 record still lists
NCT05988619 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 3 interventions - of which Psychoeducation is the first listed.
NCT05988619 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05988619 about?
NCT05988619 is a clinical study titled "iCBT With TMS in Patients With MDD". Major Depressive Disorder (MDD) is a common mental health diagnosis. While there are many approaches to the treatment of MDD, current treatments of MDD often do not substantially reduce depressive symptoms among those in need of care. Prior research suggests that combining cognitive-behavioral thera...
What is the current status of trial NCT05988619?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2021-03-21. Estimated completion is 2024-09-07.
What interventions are being tested in trial NCT05988619?
The interventions under investigation include: Psychoeducation (BEHAVIORAL), Transcranial Magnetic Stimulation (DEVICE), Internet-Based Cognitive Behavioral Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05988619?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05988619's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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