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NCT05967455 · ClinicalTrials.gov registry record · Phase 1
Homologous Re-infection With Dengue 1 or Dengue 3
A Phase 1 study, sponsored by State University of New York - Upstate Medical University.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT05967455 is a Phase 1 study that has completed, run by State University of New York - Upstate Medical University. The registered enrollment target is 9 participants.
The verdict
NCT05967455, a Phase 1 study, has completed, sponsored by State University of New York - Upstate Medical University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
Previous studies with one dengue infection in a controlled environment at Upstate generated data that has been important in understanding the clinical signs and symptoms and how a person's body reacts to dengue infection over time. This has helped investigators compare what is seen in the clinic to what is seen in areas where dengue is prevalent. The investigators want to collect similar information when a person gets the same dengue twice in a controlled environment with the hope that this will lead them to a better understanding of the disease. New participants * will receive one inoculation of dengue and then return to the clinic or be contacted by phone over 6 months; * will receive a second inoculation after 6 months and return to the clinic or be contacted by phone for three more months; * will collect saliva at home; * will allow the study team to collect blood and saliva at the clinic visits. Participants who have been in previous dengue inoculation studies at SUNY Upstate * will receive one inoculation of dengue and then return to the clinic or be contacted by phone over 6 months; * will collect saliva at home; * will allow the study team to collect blood and saliva at the clinic visits. All participants will be seen in the clinic every other day for the first three weeks after any inoculation.
Interventions
- BIOLOGICAL Dengue virus 1 Live Virus Human Challenge (DENV-1-LVHC)
- BIOLOGICAL Dengue virus 3 Live Virus Human Challenge (DENV-3-LVHC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2023-10-30 |
| Est. Completion | 2024-08-26 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05967455
The ClinicalTrials.gov registry entry for NCT05967455 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is State University of New York - Upstate Medical University, which has 113 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Dengue virus 1 Live Virus Human Challenge (DENV-1-LVHC) is the first listed.
NCT05967455 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05967455 about?
NCT05967455 is a clinical study titled "Homologous Re-infection With Dengue 1 or Dengue 3". Previous studies with one dengue infection in a controlled environment at Upstate generated data that has been important in understanding the clinical signs and symptoms and how a person's body reacts to dengue infection over time. This has helped investigators compare what is seen in the clinic to ...
What is the current status of trial NCT05967455?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2023-10-30. Estimated completion is 2024-08-26.
What interventions are being tested in trial NCT05967455?
The interventions under investigation include: Dengue virus 1 Live Virus Human Challenge (DENV-1-LVHC) (BIOLOGICAL), Dengue virus 3 Live Virus Human Challenge (DENV-3-LVHC) (BIOLOGICAL).
Who is sponsoring clinical trial NCT05967455?
This trial is sponsored by State University of New York - Upstate Medical University, which has 113 total clinical trials registered on ClinicalTrials.gov.
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