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ACTIVE NOT RECRUITING Phase 1

First in Human Study of TORL-3-600 in Participants With Advanced Cancer

NCT05948826 · View on ClinicalTrials.gov ↗

Study Summary

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-3-600 in patients with advanced cancer

Interventions

  • DRUG TORL-3-600

Study Locations (9)

California

  • Providence Medical Foundation — Fullerton
  • UCLA - JCCC Clinical Research Unit — Los Angeles

Colorado

  • Sarah Cannon Research Institute — Denver

Indiana

  • Fort Wayne Medical Oncology and Hematology Inc. — Fort Wayne

Missouri

  • Washington University School of Medicine-Siteman Cancer Center — St Louis

Tennessee

  • Sarah Cannon Research Institute-Tennessee — Nashville

Texas

  • Mary Crowley Cancer Research — Dallas

Ontario

  • University Health Network, Princess Margaret Cancer Centre — Toronto

Quebec

  • McGill University Health Centre — Montreal

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2023-09-29
Est. Completion 2026-09-15
Phase Phase 1

Sponsor

TORL Biotherapeutics

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05948826

The ClinicalTrials.gov registry entry for NCT05948826 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is TORL Biotherapeutics, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention — of which TORL-3-600 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05948826 reports 9 study locations spanning 8 distinct geographic areas — top geographies include California, Colorado, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05948826 about?

NCT05948826 is a clinical study titled "First in Human Study of TORL-3-600 in Participants With Advanced Cancer". This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-3-600 in patients with advanced cancer

What is the current status of trial NCT05948826?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2023-09-29. Estimated completion is 2026-09-15.

What conditions does trial NCT05948826 study?

This clinical trial studies the following conditions: Colorectal Cancer, Advanced Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05948826?

The interventions under investigation include: TORL-3-600 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05948826?

This trial is sponsored by TORL Biotherapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05948826 being conducted?

This trial has 9 study locations across California, Colorado, Indiana, Missouri, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial