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NCT05947838 · ClinicalTrials.gov registry record · NA
A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma
A NA study of Colorectal and Appendiceal Adenocarcinoma, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT05947838: Recruiting NA study of Colorectal and Appendiceal Adenocarcinoma, sponsored by M.D. Anderson Cancer Center.
NCT05947838 is a NA study of Colorectal and Appendiceal Adenocarcinoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05947838, a NA study of Colorectal and Appendiceal Adenocarcinoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
To learn if circulating tumor DNA (ctDNA) testing before cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) can show if patients have a low or high risk of the disease returning and help doctors decide if less or more intense chemotherapy is needed as treatment before surgery. ctDNA testing measures the amount of tumor DNA (genetic information) in the blood.
Conditions Studied
Interventions
- PROCEDURE Circulating tumoral DNA directed neoadjuvant therapy arm
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2023-12-04 |
| Est. Completion | 2026-04-30 |
| Phase | NA |
What NCT05947838 shows while recruiting
NCT05947838 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Colorectal appearing as the primary indexed condition, and to 1 intervention - of which Circulating tumoral DNA directed neoadjuvant therapy arm is the first listed.
NCT05947838 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05947838 about?
NCT05947838 is a clinical study titled "A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma". To learn if circulating tumor DNA (ctDNA) testing before cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) can show if patients have a low or high risk of the disease returning and help doctors decide if less or more intense chemotherapy is needed as treatment b...
What is the current status of trial NCT05947838?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2023-12-04. Estimated completion is 2026-04-30.
What conditions does trial NCT05947838 study?
This clinical trial studies the following conditions: Colorectal, Appendiceal Adenocarcinoma.
What interventions are being tested in trial NCT05947838?
The interventions under investigation include: Circulating tumoral DNA directed neoadjuvant therapy arm (PROCEDURE).
Who is sponsoring clinical trial NCT05947838?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05947838 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05947838's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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