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NCT05935332 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma
A Phase 2 study, sponsored by RAPT Therapeutics.
- Terminated
- Registry status
- Phase 2
- Development phase
- 38
- Enrollment target
NCT05935332: Clinical Trial Phase 2 study, sponsored by RAPT Therapeutics.
NCT05935332 is a Phase 2 study that was terminated before completion, run by RAPT Therapeutics. The registered enrollment target is 38 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05935332, a Phase 2 study, was terminated before completion, sponsored by RAPT Therapeutics.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 38 participants
- Enrollment target
Study Summary
Randomized, multi-center, double-blind, placebo-controlled, parallel group, proof of-concept study with RPT193 in subjects with T2-high, moderate-to-severe asthma who are partially controlled on medium or high doses of inhaled corticosteroids (ICS) in combination with long-acting beta 2 agonist (LABA).
Primary Outcome
Participants experiencing LOAC events; ≥ 30% reduction in peak expiratory flow; ≥ 6 additional inhalations of short-acting beta 2 agonist; increase by factor of 4 or more of inhaled corticosteroids; and/or evidence of a severe asthma exacerbation
Interventions
- OTHER Placebo
- DRUG RPT193
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2023-07-05 |
| Est. Completion | 2024-06-21 |
| Phase | Phase 2 |
Why NCT05935332 stopped before completion
NCT05935332 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05935332 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05935332 about?
NCT05935332 is a clinical study titled "Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma". Randomized, multi-center, double-blind, placebo-controlled, parallel group, proof of-concept study with RPT193 in subjects with T2-high, moderate-to-severe asthma who are partially controlled on medium or high doses of inhaled corticosteroids (ICS) in combination with long-acting beta 2 agonist (LAB...
What is the current status of trial NCT05935332?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 38 participants. The study started on 2023-07-05. Estimated completion is 2024-06-21.
What interventions are being tested in trial NCT05935332?
The interventions under investigation include: Placebo (OTHER), RPT193 (DRUG).
Who is sponsoring clinical trial NCT05935332?
This trial is sponsored by RAPT Therapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05935332's enrollment target sits among peer trials
38 1467th of 2000 higher than 517 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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