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NCT05924152 · ClinicalTrials.gov registry record · Phase 1
A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib
A Phase 1 study, sponsored by Mirati Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT05924152: Completed Phase 1 study, sponsored by Mirati Therapeutics.
NCT05924152 is a Phase 1 study that has completed, run by Mirati Therapeutics. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05924152, a Phase 1 study, has completed, sponsored by Mirati Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
A Phase 1, Open-label, One-sequence Crossover Study to Investigate the Effect of a Breast Cancer Resistance Protein Inhibitor on the Single-dose Pharmacokinetics of Adagrasib in Healthy Adult Subjects
Primary Outcome
Area under the plasma concentration-time curve (AUC) from time zero to infinity (AUC∞)
Interventions
- DRUG Adagrasib
- DRUG Eltrombopag + adagrasib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2023-06-29 |
| Est. Completion | 2023-08-17 |
| Phase | Phase 1 |
What the finished NCT05924152 record still lists
NCT05924152 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which Adagrasib is the first listed.
NCT05924152 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05924152 about?
NCT05924152 is a clinical study titled "A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib". A Phase 1, Open-label, One-sequence Crossover Study to Investigate the Effect of a Breast Cancer Resistance Protein Inhibitor on the Single-dose Pharmacokinetics of Adagrasib in Healthy Adult Subjects
What is the current status of trial NCT05924152?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2023-06-29. Estimated completion is 2023-08-17.
What interventions are being tested in trial NCT05924152?
The interventions under investigation include: Adagrasib (DRUG), Eltrombopag + adagrasib (DRUG).
Who is sponsoring clinical trial NCT05924152?
This trial is sponsored by Mirati Therapeutics, which has 49 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05924152's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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