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NCT05913557 · ClinicalTrials.gov registry record · Early Phase 1
Radical Openness for Adolescents Pilot
A Early Phase 1 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 61
- Enrollment target
NCT05913557: Completed Early Phase 1 study, sponsored by Washington University School of Medicine.
NCT05913557 is a Early Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 61 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (15% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05913557, a Early Phase 1 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 61 participants
- Enrollment target
Study Summary
Heightened performance monitoring and overcontrol (HPM/OC) is characterized by inflexibility, a need for control, perfectionism, anxious apprehension and high error monitoring. HPM/OC is a cross-diagnostic (transdiagnostic) characteristic occurring across multiple forms of psychiatric illness that emerge in adolescence, including anorexia nervosa (AN), obsessive compulsive disorder (OCD) and social anxiety disorder. This study characterizes behavioral and neural HPM/OC in healthy adolescents and adolescents with disorders characterized by HPM/OC, including AN and related eating disorders and anxiety, depressive and obsessive compulsive disorders. We then examine feasibility of a novel treatment for HPM/OC in adolescents, examining recruitment feasibility, exploration of the mechanism of HPM/OC and examining whether treatment is able to target neural and behavioral HPM/OC.
Primary Outcome
ERN data is obtained during electroencephalogram (EEG) sessions during which participants engage in several behavioral tasks. These tasks include Flankers (participant must quickly press an arrow key that corresponds to the center arrowhead depicted on the screen)
Interventions
- BEHAVIORAL Radically Open Dialectical Behavior Therapy (RO DBT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2020-08-11 |
| Est. Completion | 2022-02-28 |
| Phase | Early Phase 1 |
What the finished NCT05913557 record still lists
NCT05913557 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (15% higher).
The record links to 0 conditions, and to 1 intervention - of which Radically Open Dialectical Behavior Therapy (RO DBT) is the first listed.
NCT05913557 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05913557 about?
NCT05913557 is a clinical study titled "Radical Openness for Adolescents Pilot". Heightened performance monitoring and overcontrol (HPM/OC) is characterized by inflexibility, a need for control, perfectionism, anxious apprehension and high error monitoring. HPM/OC is a cross-diagnostic (transdiagnostic) characteristic occurring across multiple forms of psychiatric illness that e...
What is the current status of trial NCT05913557?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 61 participants. The study started on 2020-08-11. Estimated completion is 2022-02-28.
What interventions are being tested in trial NCT05913557?
The interventions under investigation include: Radically Open Dialectical Behavior Therapy (RO DBT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05913557?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05913557's enrollment target sits among peer trials
61 397th of 2000 higher than 1,599 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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