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NCT05903495 · ClinicalTrials.gov registry record · NA
Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder
A NA study, sponsored by West Virginia University.
- Completed
- Registry status
- NA
- Development phase
- 1
- Enrollment target
NCT05903495: Completed NA study, sponsored by West Virginia University.
NCT05903495 is a NA study that has completed, run by West Virginia University. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05903495, a NA study, has completed, sponsored by West Virginia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 1 participants
- Enrollment target
Study Summary
The purpose of this clinical study is to investigate the safety, tolerability, and feasibility of Deep Brain Stimulation (DBS) of the nucleus accumbens (NAc) and ventral internal capsule (VC) for participants with treatment refractory opioid use disorder (OUD) who have cognitive, behavioral, and functional disability.
Primary Outcome
Incidence of Study-Emergent Adverse Events. The safety/tolerability primary endpoint will be assessed comparing Grade 3 and 4 adverse events between the Active (DBS-ON) and Sham (DBS-OFF) arms throughout Phase IV (Outpatient Week 12). We will also categorize adverse events by organ system and assess relatedness to any aspect of this proof-of-concept study. Statistical tests will be performed at the request of the Data and Safety Monitoring Board (DSMB).
Interventions
- DEVICE Deep Brain Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2023-07-01 |
| Est. Completion | 2024-06-28 |
| Phase | NA |
What the finished NCT05903495 record still lists
NCT05903495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Deep Brain Stimulation is the first listed.
NCT05903495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05903495 about?
NCT05903495 is a clinical study titled "Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder". The purpose of this clinical study is to investigate the safety, tolerability, and feasibility of Deep Brain Stimulation (DBS) of the nucleus accumbens (NAc) and ventral internal capsule (VC) for participants with treatment refractory opioid use disorder (OUD) who have cognitive, behavioral, and fun...
What is the current status of trial NCT05903495?
This trial is currently completed. It is a NA study. The enrollment target is 1 participants. The study started on 2023-07-01. Estimated completion is 2024-06-28.
What interventions are being tested in trial NCT05903495?
The interventions under investigation include: Deep Brain Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05903495?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05903495's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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