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NCT05898087 · ClinicalTrials.gov registry record · Phase 4
Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty
A Phase 4 study of Postoperative Pain and Macromastia, sponsored by Connecticut Children's Medical Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 128
- Enrollment target
- 2
- Study locations
NCT05898087: Recruiting Phase 4 study of Postoperative Pain and Macromastia, sponsored by Connecticut Children's Medical Center.
NCT05898087 is a Phase 4 study of Postoperative Pain and Macromastia that is actively recruiting participants, run by Connecticut Children's Medical Center. The registered enrollment target is 128 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (45% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05898087, a Phase 4 study of Postoperative Pain and Macromastia, is actively recruiting participants, sponsored by Connecticut Children's Medical Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 128 participants
- Enrollment target
- 2
- Study locations
Study Summary
The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 30cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 30cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.
Primary Outcome
Post-operative pain score will be patient reported on a rating scale of 1-10. This will be recorded by the PACU nurse upon admission and upon discharge from the PACU. Patients will subsequently record a daily pain score in a home log daily until their 1 week follow-up visit. Scores will be recorded using the home log provided by the patient. We will also utilize chart review to record PACU pain score from the immediate post-operative time period.
Conditions Studied
Interventions
- DRUG Saline
- DRUG Marcaine 0.25 % Injectable Solution
Study Locations (2)
Connecticut
- Connecticut Children's - Farmington
- Connecticut Children's - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2022-04-01 |
| Est. Completion | 2026-04-01 |
| Phase | Phase 4 |
What NCT05898087 shows while recruiting
NCT05898087 is an interventional study that assigns participants to a tested intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (45% lower).
The record links to 2 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT05898087 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05898087 about?
NCT05898087 is a clinical study titled "Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty". The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intra...
What is the current status of trial NCT05898087?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 128 participants. The study started on 2022-04-01. Estimated completion is 2026-04-01.
What conditions does trial NCT05898087 study?
This clinical trial studies the following conditions: Postoperative Pain, Macromastia.
What interventions are being tested in trial NCT05898087?
The interventions under investigation include: Saline (DRUG), Marcaine 0.25 % Injectable Solution (DRUG).
Who is sponsoring clinical trial NCT05898087?
This trial is sponsored by Connecticut Children's Medical Center, which has 55 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05898087 being conducted?
This trial has 2 study locations across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05898087's enrollment target sits among peer trials
128 41st of 120 higher than 79 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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