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NCT05890677 · ClinicalTrials.gov registry record · NA
The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema
A NA study of Lymphedema, Breast Cancer, sponsored by University Hospital, Basel, Switzerland.
- Recruiting
- Registry status
- NA
- Development phase
- 280
- Enrollment target
- 20
- Study locations
NCT05890677: Recruiting NA study of Lymphedema, Breast Cancer, sponsored by University Hospital, Basel, Switzerland.
NCT05890677 is a NA study of Lymphedema, Breast Cancer that is actively recruiting participants, run by University Hospital, Basel, Switzerland. The registered enrollment target is 280 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05890677, a NA study of Lymphedema, Breast Cancer, is actively recruiting participants, sponsored by University Hospital, Basel, Switzerland.
- RECRUITING
- Registry status
- NA
- Development phase
- 280 participants
- Enrollment target
- 20
- Study locations
Study Summary
The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization (and therefore about one year after surgery) compared to conservative treatment only for patients with chronic lymphedema (LE)
Primary Outcome
The LYMPH-ICF-UL-Questionnaire (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema) is a widely used, rigorously developed, and validated patient-reported outcome (PRO) instrument for chronic breast cancer-related lymphedema. It assesses the impairments in function, activity limitations and participation restrictions of patients with upper limb lymphedema (LE). Consisting of 29 items (questions) across five different domains, each item is scored on a VAS (visual
Conditions Studied
Interventions
- PROCEDURE Surgical Intervention
- PROCEDURE Conservative Complex Physical Decongestion Therapy
Study Locations (20)
Other
- Krankenhaus Göttlicher Heiland GmbH - Vienna
- University of Ghent - Ghent
- McGill University, Royal Victoria Hospital - Montreal
- University of British Columbia, Gordon and Leslie Diamond Health Care Centre - Vancouver
- BG Universitätsklinikum Bergmannsheil Bochum - Bochum
- Sana Kliniken Düsseldorf - Düsseldorf
- Uniklinikum Erlangen - Erlangen
- KEM Evang. Kliniken Essen-Mitte - Essen
- BG Klinik Frankfurt am Main - Frankfurt
- Universitätsklinikum Freiburg, Klinik für Plastische und Handchirurgie - Freiburg im Breisgau
- BG Klinik Ludwigshafen - Ludwigshafen am Rhein
- Klinikum Nürnberg - Nuremberg
- Caritas Krankenhaus St. Josef/ Uniklinik Regensburg - Regensburg
- Papageorgiou Hospital of Thessaloniki - Thessaloniki
Connecticut
- Yale School of Medicine - New Haven
Massachusetts
- Harvard Medical School - Boston
Missouri
- Washington University School of Medicine in St. Louis - St Louis
New York
- Mayo Clinic - Rochester
Jette
- Brussels University Hospital - Brussels
Curitiba
- Hospital Erasto Gaertner - Paraná
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2023-07-14 |
| Est. Completion | 2036-06 |
| Phase | NA |
What NCT05890677 shows while recruiting
NCT05890677 is an interventional study that assigns participants to a tested intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Lymphedema, Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Surgical Intervention is the first listed.
NCT05890677 names 20 study sites across 7 states, led by Other, Connecticut, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05890677 about?
NCT05890677 is a clinical study titled "The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema". The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization (and therefore about one year after surgery) compared to conservative ...
What is the current status of trial NCT05890677?
This trial is currently recruiting. It is a NA study. The enrollment target is 280 participants. The study started on 2023-07-14. Estimated completion is 2036-06.
What conditions does trial NCT05890677 study?
This clinical trial studies the following conditions: Lymphedema, Breast Cancer.
What interventions are being tested in trial NCT05890677?
The interventions under investigation include: Surgical Intervention (PROCEDURE), Conservative Complex Physical Decongestion Therapy (PROCEDURE).
Who is sponsoring clinical trial NCT05890677?
This trial is sponsored by University Hospital, Basel, Switzerland, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05890677 being conducted?
This trial has 20 study locations across Connecticut, Massachusetts, Missouri, New York, Jette. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05890677's enrollment target sits among peer trials
280 380th of 2000 higher than 1,620 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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