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NCT05890105 · ClinicalTrials.gov registry record · Phase 1
A Study to Learn About the Study Medicine PF-07853578 and How it Acts in the Bodies of Healthy Adults
A Phase 1 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT05890105: Completed Phase 1 study, sponsored by Pfizer.
NCT05890105 is a Phase 1 study that has completed, run by Pfizer. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05890105, a Phase 1 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
The purposes of this study are: * To see how the new medicine (PF-07853578) under study is tolerated. And if there are any important side effects. And, how people feel after taking single increasing amount of the medicine by mouth. * To measure the amount of study medicine in your blood after the medicine is taken by mouth. This study is seeking for participants who: * are females of 18 to 65 years old and are not able to give birth to a child. * are males of 18 to 65 years old. * have body mass index of 16 to 31 kilograms per meter squared. * have a total body weight of more than 50 kilograms (110 pounds). Participants will be randomly selected to receive either study medicine (PF-07853578) or placebo (a pill that has no medicine in it). Participants may receive up to 4 amounts of study medicine and up to 2 amounts of placebo.
Primary Outcome
An adverse event (AE) is any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An adverse event is considered a TEAE if the event started during the effective duration of treatment. All events that started on or after the first dosing day and time/start time, if collected, but before the end of the study were flagged as TEAEs. The algorithm did not consider
Interventions
- DRUG Placebo
- DRUG PF-07853578
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2023-06-02 |
| Est. Completion | 2023-12-01 |
| Phase | Phase 1 |
What the finished NCT05890105 record still lists
NCT05890105 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05890105 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05890105 about?
NCT05890105 is a clinical study titled "A Study to Learn About the Study Medicine PF-07853578 and How it Acts in the Bodies of Healthy Adults". The purposes of this study are: * To see how the new medicine (PF-07853578) under study is tolerated. And if there are any important side effects. And, how people feel after taking single increasing amount of the medicine by mouth. * To measure the amount of study medicine in your blood after the m...
What is the current status of trial NCT05890105?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2023-06-02. Estimated completion is 2023-12-01.
What interventions are being tested in trial NCT05890105?
The interventions under investigation include: Placebo (DRUG), PF-07853578 (DRUG).
Who is sponsoring clinical trial NCT05890105?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05890105's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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