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NCT05888506 · ClinicalTrials.gov registry record · NA
Ketone Ester Supplementation and Nocturnal Blood Pressure
A NA study, sponsored by Georgia Southern University.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT05888506 is a NA study that has completed, run by Georgia Southern University. The registered enrollment target is 40 participants.
The verdict
NCT05888506, a NA study, has completed, sponsored by Georgia Southern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Cardiovascular disease (CVD) is the number one cause of death globally and high blood pressure (i.e., hypertension) is the leading modifiable risk factor for CVD and all-cause mortality. Advancing age is the primary risk factor for hypertension and CVD. Moreover, compared to younger adults, older adults exhibit reduced nocturnal dipping of blood pressure resulting in elevated nighttime blood pressure values, which are a better predictor of cardiovascular outcomes than daytime blood pressure. Intriguingly, recently published rodent data suggests that ketone supplementation protects against hypertension, blood vessel dysfunction, and kidney injury. Whether ketone supplementation provides vascular health benefits in humans remains to be determined. Therefore, the investigations seek to conduct an acute ketone supplementation study to determine whether ketone supplementation may restore a more healthy nighttime blood pressure phenotype in middle-aged and older adults. The investigations will also determine whether ketone supplementation influences nocturnal heart rate variability, a non-invasive of autonomic function that may be influenced by ketone supplementation in a manner that influences blood pressure.
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Ketone Ester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-08-01 |
| Est. Completion | 2023-10-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05888506
The ClinicalTrials.gov registry entry for NCT05888506 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Georgia Southern University, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05888506 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05888506 about?
NCT05888506 is a clinical study titled "Ketone Ester Supplementation and Nocturnal Blood Pressure". Cardiovascular disease (CVD) is the number one cause of death globally and high blood pressure (i.e., hypertension) is the leading modifiable risk factor for CVD and all-cause mortality. Advancing age is the primary risk factor for hypertension and CVD. Moreover, compared to younger adults, older ad...
What is the current status of trial NCT05888506?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2023-08-01. Estimated completion is 2023-10-03.
What interventions are being tested in trial NCT05888506?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Ketone Ester (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05888506?
This trial is sponsored by Georgia Southern University, which has 4 total clinical trials registered on ClinicalTrials.gov.
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