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NCT05869500 · ClinicalTrials.gov registry record · NA
The Boston Pace Study
A NA study, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT05869500: Active NA study, sponsored by Massachusetts General Hospital.
NCT05869500 is a NA study that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 100 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05869500, a NA study, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
Right ventricular (RV) pacing can cause left ventricular systolic dysfunction in 10- 20% of patients. Biventricular pacing had previously been shown to prevent left ventricular systolic dysfunction. However, implantation of coronary sinus lead increases procedural risk and can be limited by higher threshold and phrenic nerve capture. HIS pacing has been evaluated as an alternative pacing strategy, but its routine use was limited by difficulty of the procedure, success rate and high pacing threshold. Left bundle branch area pacing (LBBAP) is a promising physiologic pacing technique that has been proposed as a pacing strategy to prevent pacing induced cardiomyopathy and for treatment of desynchrony in heart failure. LBBAP has been adopted widely and performed routinely on patients with AV block. Currently, it is up to the discretion of the proceduralist whether LBBAP is performed given that there is lack of evidence to guide pacing strategies.
Interventions
- DEVICE Left Bundle Branch Area Pacemaker
- DEVICE Right Ventricular Pacemaker
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-05-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05869500
The ClinicalTrials.gov registry entry for NCT05869500 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Left Bundle Branch Area Pacemaker is the first listed.
NCT05869500 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05869500 about?
NCT05869500 is a clinical study titled "The Boston Pace Study". Right ventricular (RV) pacing can cause left ventricular systolic dysfunction in 10- 20% of patients. Biventricular pacing had previously been shown to prevent left ventricular systolic dysfunction. However, implantation of coronary sinus lead increases procedural risk and can be limited by higher t...
What is the current status of trial NCT05869500?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-05-01. Estimated completion is 2026-06-30.
What interventions are being tested in trial NCT05869500?
The interventions under investigation include: Left Bundle Branch Area Pacemaker (DEVICE), Right Ventricular Pacemaker (DEVICE).
Who is sponsoring clinical trial NCT05869500?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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