Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05867654 · ClinicalTrials.gov registry record · Phase 4
Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis
A Phase 4 study, sponsored by University of Louisville.
- Not yet
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
NCT05867654: Clinical Trial Phase 4 study, sponsored by University of Louisville.
NCT05867654 is a Phase 4 study that has not yet begun recruiting, run by University of Louisville. The registered enrollment target is 100 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05867654, a Phase 4 study, has not yet begun recruiting, sponsored by University of Louisville.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
Study Summary
The goal of this clinical trial is compare the efficacy of oral and IV antibiotics in the treatment of orofacial osteomyelitis. The main question it aims to answer is: Are oral antibiotics as effective as IV antibiotics in the treatment of orofacial osteomyelitis. Participants, once diagnosed with osteomyelitis, will be started on oral antibiotics for their treatment. Participants will follow up with oral and maxillofacial surgery clinic accordingly and their progression and compliance will be monitored.
Interventions
- DRUG Amoxicillin-clavulanate 875mg/125mg q12hrs
- DRUG oral clindamycin 300mg q6hrs
- DRUG Levofloxacin 750mg QID
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-07-31 |
| Est. Completion | 2025-12 |
| Phase | Phase 4 |
What is known before NCT05867654 opens enrollment
NCT05867654 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 3 interventions - of which Amoxicillin-clavulanate 875mg/125mg q12hrs is the first listed.
NCT05867654 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05867654 about?
NCT05867654 is a clinical study titled "Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis". The goal of this clinical trial is compare the efficacy of oral and IV antibiotics in the treatment of orofacial osteomyelitis. The main question it aims to answer is: Are oral antibiotics as effective as IV antibiotics in the treatment of orofacial osteomyelitis. Participants, once diagnosed with ...
What is the current status of trial NCT05867654?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2024-07-31. Estimated completion is 2025-12.
What interventions are being tested in trial NCT05867654?
The interventions under investigation include: Amoxicillin-clavulanate 875mg/125mg q12hrs (DRUG), oral clindamycin 300mg q6hrs (DRUG), Levofloxacin 750mg QID (DRUG).
Who is sponsoring clinical trial NCT05867654?
This trial is sponsored by University of Louisville, which has 217 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05867654's enrollment target sits among peer trials
100 770th of 2000 higher than 1,148 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI