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NCT05846880 · ClinicalTrials.gov registry record · Early Phase 1

VitD3 Supplementation in Patients With Multiple Myeloma

A Early Phase 1 study of Multiple Myeloma, sponsored by Amany Keruakous, MD, MS..

Recruiting
Registry status
Early Phase 1
Development phase
100
Enrollment target
1
Study location

NCT05846880 is a Early Phase 1 study of Multiple Myeloma that is actively recruiting participants, run by Amany Keruakous, MD, MS.. The registered enrollment target is 100 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05846880, a Early Phase 1 study of Multiple Myeloma, is actively recruiting participants, sponsored by Amany Keruakous, MD, MS..

RECRUITING
Registry status
Early Phase 1
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to evaluate post-transplant immune reconstitution and lymphocyte recovery as well as the 3-year progression-free survival of patients with multiple myeloma in two treatment arms. One arm will receive Maintenance Vitamin D and the other arm will receive no maintenance Vitamin D prior to ASCT. Post ASCT arm 1 will have lenalidomide and maintenance VitD, and arm 2 will receive lenalidomide and no maintenance VitD. This clinical trial will also evaluate the overall response rate and survival for both treatment arms.

Conditions Studied

Interventions

  • DRUG Lenalidomide
  • DRUG Maintenance Vitamin D
  • DRUG No maintenance Vitamin D

Study Locations (1)

Georgia

  • Georgia Cancer Center at Augusta University - Augusta

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2024-12-01
Est. Completion 2028-05
Phase Early Phase 1

Sponsor

Amany Keruakous, MD, MS.

1 total trials

What the Registry Record Tells You About NCT05846880

The ClinicalTrials.gov registry entry for NCT05846880 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (82% lower). The listed sponsor is Amany Keruakous, MD, MS., which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Lenalidomide is the first listed.

NCT05846880 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.

Frequently Asked Questions

What is clinical trial NCT05846880 about?

NCT05846880 is a clinical study titled "VitD3 Supplementation in Patients With Multiple Myeloma". The goal of this clinical trial is to evaluate post-transplant immune reconstitution and lymphocyte recovery as well as the 3-year progression-free survival of patients with multiple myeloma in two treatment arms. One arm will receive Maintenance Vitamin D and the other arm will receive no maintenan...

What is the current status of trial NCT05846880?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2024-12-01. Estimated completion is 2028-05.

What conditions does trial NCT05846880 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT05846880?

The interventions under investigation include: Lenalidomide (DRUG), Maintenance Vitamin D (DRUG), No maintenance Vitamin D (DRUG).

Who is sponsoring clinical trial NCT05846880?

This trial is sponsored by Amany Keruakous, MD, MS., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05846880 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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