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NCT05846646 · ClinicalTrials.gov registry record · Phase 2
Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC
A Phase 2 study, sponsored by ImmuneSensor Therapeutics.
- Terminated
- Registry status
- Phase 2
- Development phase
- 6
- Enrollment target
NCT05846646: Clinical Trial Phase 2 study, sponsored by ImmuneSensor Therapeutics.
NCT05846646 is a Phase 2 study that was terminated before completion, run by ImmuneSensor Therapeutics. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05846646, a Phase 2 study, was terminated before completion, sponsored by ImmuneSensor Therapeutics.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 6 participants
- Enrollment target
Study Summary
Phase 2, open-label, multicenter, randomized study comparing the safety and efficacy of personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) combined with immune checkpoint inhibitor (ICI) immunotherapy (PULSAR-ICI) + IMSA101 and PULSAR-ICI alone in patients with NSCLC or RCC
Primary Outcome
Progression-free rate at 18 months
Interventions
- DRUG IMSA101
- DRUG Immune checkpoint inhibitor
- RADIATION PULSAR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2023-06-28 |
| Est. Completion | 2024-09-16 |
| Phase | Phase 2 |
Why NCT05846646 stopped before completion
NCT05846646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 3 interventions - of which IMSA101 is the first listed.
NCT05846646 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05846646 about?
NCT05846646 is a clinical study titled "Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC". Phase 2, open-label, multicenter, randomized study comparing the safety and efficacy of personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) combined with immune checkpoint inhibitor (ICI) immunotherapy (PULSAR-ICI) + IMSA101 and PULSAR-ICI alone in patients with NSCLC or RCC
What is the current status of trial NCT05846646?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2023-06-28. Estimated completion is 2024-09-16.
What interventions are being tested in trial NCT05846646?
The interventions under investigation include: IMSA101 (DRUG), Immune checkpoint inhibitor (DRUG), PULSAR (RADIATION).
Who is sponsoring clinical trial NCT05846646?
This trial is sponsored by ImmuneSensor Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05846646's enrollment target sits among peer trials
6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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