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NCT05846451 · ClinicalTrials.gov registry record · Early Phase 1

Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints

A Early Phase 1 study of Herbal Interaction, sponsored by Washington State University.

Recruiting
Registry status
Early Phase 1
Development phase
16
Enrollment target
1
Study location

NCT05846451 is a Early Phase 1 study of Herbal Interaction that is actively recruiting participants, run by Washington State University. The registered enrollment target is 16 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05846451, a Early Phase 1 study of Herbal Interaction, is actively recruiting participants, sponsored by Washington State University.

RECRUITING
Registry status
Early Phase 1
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to investigate whether the botanical product kratom affects how the body processes the opioid drug oxycodone. The main research questions to be answered are two-fold: 1. How does kratom affect the manner in which oxycodone is metabolized (broken down and removed) by the body? 2. Does kratom change the effects oxycodone exerts on the body? Healthy adult participants will complete four study arms, during which they will be given the following: * Kratom (as a tea) * A single dose of oxycodone (as a tablet) * Kratom tea and a single dose of oxycodone * Kratom tea for four days, then kratom tea and a single dose of oxycodone

Conditions Studied

Interventions

  • DRUG Oxycodone
  • DIETARY_SUPPLEMENT Kratom

Study Locations (1)

Washington

  • Washington State University College of Pharmacy and Pharmaceutical Sciences - Spokane

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2023-06-01
Est. Completion 2025-05-01
Phase Early Phase 1

Sponsor

Washington State University

64 total trials

What the Registry Record Tells You About NCT05846451

The ClinicalTrials.gov registry entry for NCT05846451 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington State University, which has 64 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Herbal Interaction appearing as the primary indexed condition, and to 2 interventions - of which Oxycodone is the first listed.

NCT05846451 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT05846451 about?

NCT05846451 is a clinical study titled "Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints". The goal of this study is to investigate whether the botanical product kratom affects how the body processes the opioid drug oxycodone. The main research questions to be answered are two-fold: 1. How does kratom affect the manner in which oxycodone is metabolized (broken down and removed) by the bo...

What is the current status of trial NCT05846451?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 16 participants. The study started on 2023-06-01. Estimated completion is 2025-05-01.

What conditions does trial NCT05846451 study?

This clinical trial studies the following conditions: Herbal Interaction.

What interventions are being tested in trial NCT05846451?

The interventions under investigation include: Oxycodone (DRUG), Kratom (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT05846451?

This trial is sponsored by Washington State University, which has 64 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05846451 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.