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NCT05846282 · ClinicalTrials.gov registry record · NA

Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience

A NA study of Allostatic Load and Internalizing Mental Health Symptoms, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
504
Enrollment target
1
Study location

NCT05846282: Recruiting NA study of Allostatic Load and Internalizing Mental Health Symptoms, sponsored by University of California, Los Angeles.

NCT05846282 is a NA study of Allostatic Load and Internalizing Mental Health Symptoms that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 504 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05846282, a NA study of Allostatic Load and Internalizing Mental Health Symptoms, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
504 participants
Enrollment target
1
Study location

Study Summary

Students who 'strive' to rise above significant stressors to achieve academic success are considered 'resilient'. However, youths' resilience in one domain (i.e. academic) can come at a cost in other domains including physical and mental health morbidities that are under-identified and under-treated. Previous research suggests that individuals from populations experiencing documented health disparities who exhibit a "striving persistent behavioral style" in the face of stress evince later health morbidities. Ironically, the same self-regulatory skills that promote academic achievement amid chronic stress can also result in physiological dysregulation that harms health and mental health. Self-regulatory processes that involve emotion suppression, experiential avoidance, and unmodulated perseverance can culminate in allostatic load which fuels health disparities and internalizing symptoms of depression and anxiety. The proposed mechanistic trial will utilize mindfulness training to permit examination of questions about the causal role of emotion regulation strategies linked to the striving persistent behavioral style in driving mental health and health morbidities among individuals from populations experiencing documented health disparities. The proposed Project STRIVE (STudents RIsing aboVE) will identify students who are academically resilient in the face of stress and will offer a tailored mindfulness intervention targeting self-regulation processes as a putative mechanism to interrupt the links between the striving persistent behavioral style and negative health outcomes. Investigators propose a multisite randomized trial randomizing 504 high achieving Black, Latinx, or Asian America/Pacific Islander students in 18 schools to receive a mindfulness intervention or an attention control condition focused on study skills. The study will: (1) test the effects of the STRIVE intervention on putative self-regulation mechanisms (emotion suppression, experiential avoidance

Primary Outcome

The Depression, Anxiety, Stress Scales (DASS) is a set of three self-report scales designed to measure the negative emotional states of depression, anxiety, and stress. The research team will assess a change in internalizing symptoms at different timepoints. For example, from Baseline to mid-assessment, mid-assessment to post-assessment, baseline to post-assessment, and baseline to 12-month follow up. The minimum score is 0 and the maximum score is 21. Higher scores indicate greater severity o

Interventions

  • BEHAVIORAL STRIVE
  • BEHAVIORAL Study Skills

Study Locations (1)

California

  • University of California - Los Angeles

Trial Details

FieldValue
Enrollment Target 504 participants
Start Date 2023-01-09
Est. Completion 2027-06
Phase NA

What NCT05846282 shows while recruiting

NCT05846282 is an interventional study that assigns participants to a tested intervention. The registered 504 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (64% lower).

The record links to 3 conditions, with Allostatic Load appearing as the primary indexed condition, and to 2 interventions - of which STRIVE is the first listed.

NCT05846282 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05846282 about?

NCT05846282 is a clinical study titled "Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience". Students who 'strive' to rise above significant stressors to achieve academic success are considered 'resilient'. However, youths' resilience in one domain (i.e. academic) can come at a cost in other domains including physical and mental health morbidities that are under-identified and under-treated...

What is the current status of trial NCT05846282?

This trial is currently recruiting. It is a NA study. The enrollment target is 504 participants. The study started on 2023-01-09. Estimated completion is 2027-06.

What conditions does trial NCT05846282 study?

This clinical trial studies the following conditions: Allostatic Load, Internalizing Mental Health Symptoms, Health Complaints.

What interventions are being tested in trial NCT05846282?

The interventions under investigation include: STRIVE (BEHAVIORAL), Study Skills (BEHAVIORAL).

Who is sponsoring clinical trial NCT05846282?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05846282 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Allostatic Load

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05846282's enrollment target sits among peer trials

504 193rd of 2000 higher than 1,808 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05846282, the US trial registry maintained by the National Library of Medicine. NCT05846282 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.