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RECRUITING NA

Excision of Lymph Node Trial (EXCILYNT) (Mel69)

NCT05839912 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to find out if removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing cancer from coming back in the same area of the lymph node excision. The study team is also trying to find out the side effects of this type of surgery and how much the surgery impacts quality of life. In order to be eligible for this study, participants must have been diagnosed with metastatic melanoma and have one detected cancerous lymph node by imaging (CT/PET scan) or clinical examination, and are a candidate for lymph node excision.

Conditions Studied

Interventions

  • PROCEDURE Excision of clinically detected lymph node metastasis before any systemic therapy
  • PROCEDURE Excision of clinically detected lymph node metastasis after neoadjuvant systemic therapy

Study Locations (7)

Georgia

  • Emory University — Atlanta

Maryland

  • University of Maryland — Baltimore

Michigan

  • University of Michigan — Ann Arbor

New York

  • Memorial Sloan Kettering Cancer Center — New York

North Carolina

  • Duke University Health System — Durham

Pennsylvania

  • University of Pennsylvania — Philadelphia

Virginia

  • Cancer Center at the University of Virginia — Charlottesville

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2023-09-06
Est. Completion 2028-09-01
Phase NA

Sponsor

Craig L Slingluff, Jr

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05839912

The ClinicalTrials.gov registry entry for NCT05839912 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Craig L Slingluff, Jr, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Melanoma appearing as the primary indexed condition, and to 2 interventions — of which Excision of clinically detected lymph node metastasis before any systemic therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05839912 reports 7 study locations spanning 7 distinct geographic areas — top geographies include Georgia, Maryland, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05839912 about?

NCT05839912 is a clinical study titled "Excision of Lymph Node Trial (EXCILYNT) (Mel69)". The purpose of this study is to find out if removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing cancer from coming back in the same area of the lymph node excision. The study team is also trying to find out the side effects of this type of surgery and h...

What is the current status of trial NCT05839912?

This trial is currently recruiting. It is a NA study. The enrollment target is 66 participants. The study started on 2023-09-06. Estimated completion is 2028-09-01.

What conditions does trial NCT05839912 study?

This clinical trial studies the following conditions: Melanoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05839912?

The interventions under investigation include: Excision of clinically detected lymph node metastasis before any systemic therapy (PROCEDURE), Excision of clinically detected lymph node metastasis after neoadjuvant systemic therapy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05839912?

This trial is sponsored by Craig L Slingluff, Jr, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05839912 being conducted?

This trial has 7 study locations across Georgia, Maryland, Michigan, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial